HistokatFusion

HistokatFusion aggregates tumor information fo AI development and individualized therapy.

Improving tumor diagnostics by providing reliable ground truth automatically.

In computational pathology an expert has to annotate thousands of tissue sections for an AI algorithm to learn and repeat his pattern recognition task automatically. Creating manual annotations is a time-consuming and therefore expensive task that also lacks accuracy considering the interobserver variability shown between experts.

 

© Fraunhofer MEVIS

HistokatFusion is able to provide the ground truth automatically. This helps AI companies to create more accurate algorithms in less time while saving the money for an expert. Automatic ground truth generation is achieved by accurately fusing serial sections, which allows for multiple, differently stained versions of similar tissue. The additional sections contain the molecular ground truth that can be used to train an AI algorithm.

HistokatFusion has been validated on thousands of differently stained image pairs.
Its potential for the fast development of accurate AI solutions has been shown with our clinical research partners.1
It has been proven to be fast, robust and accurate in an international challenge.2

1 https://www.nature.com/articles/s41598-018-37257-4
2 HistokatFusion was ranked as the final #1 in the Automatic Non-rigid Histological Image Registration (ANHIR) challenge at the IEEE International Symposium on Biomedical Imaging (ISBI) in 2019. Winning in terms of accuracy, robustness and speed.

Meet the team behind HistokatFusion.

Contact Press / Media

Dr. rer. nat. Johannes Lotz

Fraunhofer Institute for Digital Medicine MEVIS
Maria-Goeppert-Str. 3
23562 Lübeck

Phone +49 451 3101-6118

Fax +49 451 3101-6104

Nick Weiss

Contact Press / Media

Nick Weiss

Fraunhofer Institute for Digital Medicine MEVIS
Maria-Goeppert-Str. 3
23562 Lübeck

Phone +49 451 3101-6121

Fax +49 451 3101-6104

Daniel Budelmann

Contact Press / Media

Daniel Budelmann

Fraunhofer Institute for Digital Medicine MEVIS
Maria-Goeppert-Str. 3
23562 Lübeck

Phone +49 451 3101-6124

Fax +49 451 3101-6104