Dr. Florian Weiler

  • Research Scientist
  • Computer Scientist



Weber CE, Krämer J, Wittayer M, Gregori J, Randoll S, Weiler F, Heldmann S, Roßmanith C, Platten M, Gass A, Eisele P (2022) Association of iron rim lesions with brain and cervical cord volume in relapsing multiple sclerosis. Eur Radiol 32(3):2012–2022


Kuckertz S, Weiler F, Matusche B, Lukas C, Spies L, Klein J, Heldmann S (2021) A system for fully automated monitoring of lesion evolution over time in multiple sclerosis. Proceedings of SPIE Medical Imaging: Computer-Aided Diagnosis. 115972D


Weiler F (2019) Computational tools for objective assessment in Neuroimaging. Ph.D. thesis


Galinovic I, Dicken V, Heitz J, Klein J, Puig J, Guibernau J, Kemmling A, Gellissen S, Villringer K, Neeb L, Gregori J, Weiler F, Pedraza S, Thomalla G, Fiehler J, Gerloff C, Fiebach JB (2018) Homogeneous application of imaging criteria in a multicenter trial supported by investigator training: A report from the WAKE-UP study. Eur J Radiol 104:115–119
Gregori J, Cornelissen C, S. H, and Treiber MRS, Heldmann S, Klein J, Opfer R, Spies L, Gass A, Ziemsen T, Kitzler H, Weiler F (2018) Feasibility of fully automated atrophy measurement of the upper cervical spinal cord for group analyses and patient-individual diagnosis support in MS. 34th Congress of ECTRIMS – European Committee for Treatment and Research in Multiple Sclerosis. 34th Congress of ECTRIMS – European Committee for Treatment and Research in Multiple Sclerosis (Abstract: A-0950-0023-00837)
Lippert F, Cheng B, Golsari A, Weiler F, Gregori J, Thomalla G, Klein J (2018) Exploring DeepMedic for the purpose of segmenting white matter hyperintensity lesions. Proceedings of SPIE Medical Imaging: Computer-Aided Diagnosis. 105752F:pp 1–7
Liu Y, Duan Y, Huang J, Ren Z, Liu Z, Dong H, Weiler F, Hahn HK, Shi F-D, Butzkueven H, Barkhof F, Li K (2018) Different patterns of longitudinal brain and spinal cord changes and their associations with disability progression in NMO and MS. Eur Radiol 28(1):96–103
Weiler F, Klein J, Gregori J, Spies L, Hildebrandt H, Heldmann S (2018) Fully automatic quantification of mean-upper cervical cord area: Agreement with multiple human raters. International Journal of Computer Assisted Radiology and Surgery. pp 150–151


Hagstrom IT, Schneider R, Bellenberg B, Salmen A, Weiler F, Koster O, Gold R, Lukas C (2017) Relevance of early cervical cord volume loss in the disease evolution of clinically isolated syndrome and early multiple sclerosis: a 2-year follow-up study. J Neurol 264(7):1402–1412
Hofmaier J, Haehnle J, Kurz C, Landry G, Maihöfer C, Süß P, Teichert K, Traulsen N, Brachmann C, Weiler F, Thieke C, Küfer KH, Belka C, Parodi K, Kamp F (2017) OC-0486: Multi-criterial patient positioning based on dose recalculation on scatter-corrected CBCT images. Radiotherapy and Oncology. pp 257–258
Hofmaier J, Haehnle J, Kurz C, Landry G, Maihoefer C, Schüttrumpf L, Süss P, Teichert K, Söhn M, Spahr N, Brachmann C, Weiler F, Thieke C, Küfer K-H, Belka C, Parodi K, Kamp F (2017) Multi-criterial patient positioning based on dose recalculation on scatter-corrected CBCT images. Radiother Oncol 125(3):464–469
Lutz T, Bellenberg B, Schneider R, Weiler F, Köster O, Lukas C (2017) Central Atrophy Early in Multiple Sclerosis: Third Ventricle Volumetry versus Planimetry: Central Atrophy in the Early Stages of MS. J Neuroimaging 27(3):348–354
Schneider R, Bellenberg B, Kleiter I, Gold R, Koster O, Weiler F, Hahn H, Lukas C (2017) Cervical cord and ventricle affection in neuromyelitis optica. Acta Neurol Scand 135(3):324–331
Weiler F, Hallmann M, Schwier M, Hildebrandt H, Gregori J, Spies L, Klein J, Heldmann S (2017) Fully automated detection, segmentation and quantification of mean cross-sectional area of the spinal cord. Proceedings of the 7thth joint ECTRIMS – ACTRIMS Meeting. P384
Wilhelms W, Bellenberg B, Koster O, Weiler F, Hoffmann R, Gold R, Saft C, Lukas C (2017) Progressive spinal cord atrophy in manifest and premanifest Huntington's disease. J Neurol Neurosurg Psychiatry 88(7):614–616


Liu Y, Lukas C, Steenwijk MD, Daams M, Versteeg A, Duan Y, Li K, Weiler F, Hahn HK, Wattjes MP, Barkhof F, Vrenken H (2016) Multicenter Validation of Mean Upper Cervical Cord Area Measurements from Head 3D T1-Weighted MR Imaging in Patients with Multiple Sclerosis. AJNR Am J Neuroradiol 37(4):749–754
Nijhuis R, Brachmann C, Kamp F, Landry G, Weiler F, Traulsen N, Chlebus G, Ganswindt U, Thieke C, Krass S, Belka C (2016) Validation of a novel contour mapping method to facilitate adaptive radiotherapy in head and neck cancer patients. Proceedings of 22. Jahrestagung der Deutschen Gesellschaft für Radioonkologie (DEGRO), Mannheim
Weiler F, Chlebus G, Brachmann C, Traulsen N, Waring A, Rieder C, Lassen-Schmidt B, Krass S, Hahn H (2016) A Modular Analysis Tool for Imaging-Based Clinical Research in Radiation Therapy. International Journal of Radiation Oncology*Biology*Physics. pp E418–E419


Akkad DA, Bellenberg B, Esser S, Weiler F, Epplen JT, Gold R, Lukas C, Haghikia A (2015) Multiple sclerosis risk loci correlate with cervical cord atrophy and may explain the course of disability. Neurogenetics 16(3):161–168
Liu Y, Wang J, Daams M, Weiler F, Hahn HK, Duan Y, Huang J, Ren Z, Ye J, Dong H, Vrenken H, Wattjes M, Barkhof F, Shi FD, Li K (2015) Differential Atrophy Patterns of Spinal Cord and Brain in Neuromyelitis Optica and Multiple Sclerosis. Neurology 84(14):1465–72
Madai VI, von Samson-Himmelstjerna FC, Sandow N, Weiler F, Bauer M, Vajkoczy P, Günther M, Dusek P, Von Gottberg P, Niendorf T, Wuerfel J, Sobesky J (2015) Ultrahigh-field MPRAGE Magnetic Resonance Angiography at 7.0T in patients with cerebrovascular disease. Eur J Radiol 84(12):2613–2617
Nijhuis R, Brachmann C, Weiler F, Traulsen N, Corr D, Schenk M, Ganswindt U, Thieke C, Wirtz S, Belka C (2015) PO-1092 A novel, efficient contour mapping method facilitates adaptive radiotherapy in head and neck patients. Radiotherapy and Oncology. pp S590–S591
Wang L, Strehlow J, Ruehaak J, Weiler F, Diez Y, Gubern-Mérida A, Diekmann S, Laue H, Hahn HK (2015) A fast alignment method for breast MRI follow-up studies using automated breast segmentation and current-prior registration. Proceedings of SPIE Medical Imaging: Image Processing. 941334:pp 1–8
Weiler F, Hahn HK (2015) Fast and intuitive segmentation of gyri of the human brain. Proceedings of SPIE Medical Imaging: Image-Guided Procedures, Robotic Interventions, and Modeling. 941517:pp 1–6
Weiler F, Chlebus G, Rieder C, Moltz J, Waring A, Brachmann C, Traulsen N, Corr D, Wirtz S, Krass S, Hahn HK (2015) Building Blocks for Clinical Research in Adaptive Radiotherapy. Proc. of CURAC 2015. pp 139–144
Weiler F, Daams M, Lukas C, Barkhof F, Hahn HK (2015) Highly accurate volumetry of the spinal cord. Proceedings of SPIE Medical Imaging: Image Processing. 941302:pp 1–6
Weiler F, Brachmann C, Traulsen N, Nijhuis R, Chlebus G, Schenk M, Corr D, Wirtz S, Ganswindt U, Thieke C, Belka C, Hahn HK (2015) Fast automated non-linear contour propagation for adaptive head and neck radiotherapy. MICCAI Workshop on Imaging and Computer Assistance in Radiation Therapy ICART


Corr D, Weiler F, Hoogenboom M, van Amerongen M, Fütterer JJ, Dadakova T, Bock M, Günther M, Jenne JW (2014) Software-supported Analysis of MRgFUS Therapy Outcome. FUS Foundation Symposium, Bethesda. 212
Daams M, Weiler F, Steenwijk MD, Hahn HK, Geurts JJ, Vrenken H, van Schijndel RA, Balk LJ, Tewarie PK, Tillema J-M, Killestein J, Uitdehaag BM, Barkhof F (2014) Mean upper cervical cord area (MUCCA) measurement in long-standing multiple sclerosis: Relation to brain findings and clinical disability. Mult Scler 20(14):1860–1865
Dicken V, Geisler B, Weiler F, Klein J, Guenther M, Galinovic I, Fiebach JB, Thomalla G (2014) Results from software based formal training of MR image reading in the WAKE-UP trial. European Stroke Conference (ESC)
Klein J, Weiler F, Hahn HK (2014) Probabilistic Parameter Adaption for Fiber Tracking of the Corticospinal Tract. Proc. of MICCAI DTI Tractography Challenge
Madai VI, von Samson-Himmelstjerna FC, Weiler F, Sandow N, Günther M, Vajkoczy P, Niendorf T, Wuerfel J, Sobesky J (2014) Depiction of vessel pathology in stroke imaging at 7.0T using non-contrast MPRAGE. Proceedings of the Joint Annual Meeting ISMRM-ESMRMB. 2039
van Straaten D, Hoogenboom M, van Amerongen M, Weiler F, Al Issawi J, Günther M, Fütterer J, Jenne JW (2014) A Software Tool for advanced MRgFUS Prostate Therapy Planning and Follow-Up. 14th International Symposium on Therapeutic Ultrasound


Rieder C, Brachmann C, Hofmann B, Klein J, Köhn A, Ojdanic D, Schumann C, Weiler F, Hahn HK (2013) Interactive Visualization of Neuroanatomical Data for a Hands-On Multimedia Exhibit. EuroVis Workshop on Visualization in Medicine and Life Sciences (VMLS). pp 37–41


Klein J, Weiler F, Barbieri S, Hirsch JG, Geisler G, Hahn HK (2012) Quantitative neuroimaging advances. ECR Today 2012, Saturday 3 March 23
Weiler F, Rieder C, David CA, Wald C, Hahn HK (2012) On the Value of Multi-Volume Visualization for Preoperative Planning of Cerebral AVM Surgery. Eurographics Workshop on Visual Computing for Biomedicine. pp 49–56


Klein J, Weiler F, Barbieri S, Hirsch JG, Geisler B, Hahn HK (2011) NeuroQLab – An Extendible Software Assistant for Efficient and Reproducible Evaluation of Neuroimaging Data. Proceedings of European Congress on Radiology (ECR 2011)
Weiler F, Hahn HK (2011) An interactive ROI tool for DTI fiber tracking. Proceedings of SPIE Medical Imaging: Visualization, Image-Guided Procedures, and Modeling. 796437:pp 1–7


Köhn A, Klein J, Weiler F, Peitgen HO (2009) A GPU-based Fiber Tracking Framework using Geometry Shaders. Proceedings of SPIE Medical Imaging. Orlando / USA, 72611J:1–10
Weiler F, Rexilius J, Klein J, Hahn HK (2009) NeuroQLab – A Software Assistent for Neurosurgical Planning and Quantitative Image Analysis. Lecture Notes in Informatics. Lübeck, pp 1485–1491


Weiler F, Hahn HK, Köhn A, Friman O, Klein J, Peitgen H-O (2008) Dealing with Inaccuracies in Multimodal Neurosurgical Planning – A Preliminary Concept. Proceedings of the 22nd International Congress and Exhibition of Computer Assisted Radiology and Surgery. pp 77–78
Weiler F, Köhn A, Klein J, Rieder C, Hahn HK, Peitgen H-O (2008) Kontextbezogene Visualisierung neurochirurgischer Planungsdaten. Deutscher Röntgenkongress. 261


Köhn A, Weiler F, Klein J, Konrad O, Hahn HK, Peitgen H-O (2007) State-of-the-Art Computer Graphics in Neurosurgical Planning and Risk Assessment. Eurographics Short Papers Med Prize Awards 117–120