Prof. Dr. rer. nat. Matthias Günther

  • Physicist
  • Research Scientist
  • Medical Imaging


Breutigam NJ, Hoinkiss DC, Buck MA, Mahroo A, von Samson-Himmelstjerna F, Guenther M (2020) Optimal subject-specific pCASL settings by automated inner-scan timing adaption. Proceedings of the 28th Annual Meeting of the ISMRM. 3282
Buck MA, Guenther M (2020) Towards patient specific dispersion correction for more accurate quantification in pCASL: modeling and experimental findings. Proceedings of the 28th Annual Meeting of the ISMRM. 0026
Cordes C, Konstandin S, Porter D, Günther M (2020) Portable and platform‐independent MR pulse sequence programs. Magn Reson Med 83(4):1277–1290
Hoinkiss DC, Cordes C, Konstandin S, Guenther M (2020) Event-Based Traversing of Hierarchical Sequences Allows Real-Time Execution and Arbitrary Looping in a Scanner-Independent MRI Framework. Proceedings of the 28th Annual Meeting of the ISMRM. 1043
Hoinkiss DC, Struckmann S, Werner N, Schmidt CO, Günther M, Hirsch J (2020) Long-Time Stability of Image Quality in the German National Cohort (NAKO) Imaging Study Based on Automatic Image Quality Assessment. Proceedings of the 37th Annual Scientific Meeting of the ESMRMB. L01.124
Huber J, Hoinkiss DC, Guenther M (2020) Subject-specific background suppression in 3D pseudo-continuous arterial spin labeling perfusion imaging. Proceedings of the 28th Annual Meeting of the ISMRM. 3283
Mutsaerts HJMM, Petr J, Groot P, Vandemaele P, Ingala S, Robertson AD, Václavů L, Groote I, Kuijf H, Zelaya F, O’Daly O, Hilal S, Wink AM, Kant I, Caan MWA, Morgan C, de Bresser J, Lysvik E, Schrantee A, Bjørnebekk A, Clement P, Shirzadi Z, Kuijer JPA, Wottschel V, Anazodo UC, Pajkrt D, Richard E, Bokkers RPH, Reneman L, Masellis M, Günther M, MacIntosh BJ, Achten E, Chappell MA, van Osch MJP, Golay X, Thomas DL, De Vita E, Bjørnerud A, Nederveen A, Hendrikse J, Asllani I, Barkhof F (2020) ExploreASL: An image processing pipeline for multi-center ASL perfusion MRI studies. NeuroImage 219:117031
Schipf S, Schöne G, Schmidt B, Günther K, Stübs G, Greiser KH, Bamberg F, Meinke-Franze C, Becher H, Berger K, Brenner H, Castell S, Damms-Machado A, Fischer B, Franzke C-W, Fricke J, Gastell S, Günther M, Hoffmann W, Holleczek B, Jaeschke L, Jagodzinski A, Jöckel K-H, Kaaks R, Kauczor H-U, Kemmling Y, Kluttig A, Krist L, Kurth B, Kuß O, Legath N, Leitzmann M, Lieb W, Linseisen J, Löffler M, Michels KB, Mikolajczyk R, Pigeot I, Mueller U, Peters A, Rach S, Schikowski T, Schulze MB, Stallmann C, Stang A, Swart E, Waniek S, Wirkner K, Völzke H, Pischon T, Ahrens W (2020) The baseline assessment of the German National Cohort (NAKO Gesundheitsstudie): participation in the examination modules, quality assurance, and the use of secondary data. Bundesgesundheitsbl 63(3):254–266
Strohm H, Rothlübbers S, Eickel K, Günther M (2020) Deep learning-based reconstruction of ultrasound images from raw channel data. Int J CARS 15:1487–1490


Archipovas S, Wilke RN, Konstandin S, Huber J, Hoinkiss DC, Cordes C, Breutigam NJ, Guenther M (2019) A prototype of a fully integrated environment for a collaborative work in MR sequence development for a reproducible research. Proceedings of the 27th Annual Meeting ISMRM. 0945

Joerg Matthias Günther


  • Dr. rer. nat (magna cum laude, Heidelberg University)
  • Physics Diploma (Heidelberg University)
  • Postgraduate Education Medical Physics (Heidelberg University)
  • Prediploma Economic Sciences (Fernuni Hagen)


Scientific Career

03/2016 – 12/2018

Guest Scientist at the University of California, Berkeley, USA

11/2009 – current

Professor of MR-Physics, University of Bremen

11/2009 – current

Head of MR-Imaging, Fraunhofer MEVIS, Bremen


Member of Management Board, Fraunhofer MEVIS, Bremen


Habilitation: "Non-invasive quantitative perfusion measurement in MRI: Efficient preparation and readout strategies for arterial spin labeling ", Faculty Physics, Heidelberg University

07/2004 – current

Executive Director of mediri GmbH, Heidelberg, Deutschland

07/2004 – 10/2009

Group Leader at the Neurological Clinic, University Clinic Mannheim, Heidelberg University,  Germany

02/2001 – 07/2004

Senior Scientist at Advanced MRI Technologies, LLC, Sebastopol, CA, USA

11/1999 – 11/2000

Postdoc at Deutsches Krebsforschungszentrum (German Cancer Research Center),  Heidelberg,  Germany

11/1996 – 11/1999

Doctoral Dissertation: Nicht-invasive Perfusionsmessung mit arterieller Spin-Markierung (german) at Deutsches Krebsforschungszentrum (German Cancer Research Center), Heidelberg,  Germany

08/1996 – 11/1996

Scientific Assistant at Max-Planck-Institute for Nuclear Physics, Heidelberg

08/1995 – 08/1996

Diploma, Heidelberg-Moscow ββ-Experiment am LNGS, Assergi, Italy for the Max-Planck-Institute, Heidelberg,  Germany

10/1991 – 08/1996

Studies of Physics at  Heidelberg University, Germany


11/1996 – 11/1999

Teaching Assistant, Physics for Medical classes, Heidelberg University, Heidelberg, Germany

11/1999 – 11/2000

Supervision of graduates and postgraduates at Deutsches Krebsforschungszentrum (German Cancer Research Center), Heidelberg, Germany

1998 – present

Numerous invited teaching courses at universities and laboratories world-wide (~150)

WS 2006/2007

Lecture on “Physical Basics of Medical Imaging” at Heidelberg University, Germany


Organizer and tutor of ESMRMB-course “MR lectures on Flow and Perfusion”, Copenhagen, Denmark.

11/2006 – present

Supervision of graduates and postgraduates at Neurological clinic, University hospital Mannheim, Heidelberg University, Germany


Lecture on Arterial Spin Labeling at the Joint Meeting of ISMRM and ESMRMB, Berlin, Germany.


Organizer and tutor of ESMRMB-course “MR lectures on Perfusion”, Freiburg, Germany.

WS 2007/2008

Lecture on “Physical Basics of Ultrasound Imaging” at MaReCuM, Heidelberg University, Germany

WS 2008/2009

Lecture on “Physical Basics of Ultrasound Imaging” at MaReCuM, Heidelberg University, Germany

SS 2010 - 2015, 2017 - 2020

Lecture on “Physical Basics of Medical Imaging” at University Bremen, Germany

WS 2010/2011

Lecture on “MR-Physics” at University Bremen, Germany


Lecture on Arterial Spin Labeling at the annual Meeting of ISMRM, Montreal, Canada.


Lecture on Perfusion at the annual Meeting of ISMRM, Montreal, Canada.

SS 2011 - 2012

Lecture on “Physik für Biologen” at University Bremen, Germany

SS 2011 - 2015, 2017 -2020

Lecture on “Experimentalphysik VI: Kerne und Teilchen” at University Bremen, Germany


Organizer and tutor of ESMRMB-course “MR lectures on Perfusion”, Oxford, UK.

WS 2011/2012, 2015/2016

Lecture series on “Methoden der Biophysik” at University Bremen, Germany


Tutor of “Arterial Spin Labeling for physicians” in Verona, Italy


Organizer and tutor of “Arterial Spin Labeling for physicists” in Toulouse, France


Organizer and tutor of ESMRMB-course “Lectures on MR - Measurement of perfusion and capillary exchange”, Bremen, Germany


Organizer and tutor of ESMRMB-course “Lectures on MR - MR image processing - from image data to information”, Berlin, Germany


Translucent Intensity Projection Imaging
Inventors: Oshio, K.; Guenther, M.; Feinberg, D.A.           
Filing date: 05/22/2001  
US 7020318

Susceptibility Correction and Contrast Encoding with Simultaneously Refocused MR Images
Inventors: Guenther, M.; Feinberg, D.A; Oshio, K.             
Filing date: 05/16/2002                                                                                       

Method and Apparatus for Removing Specific Stimulated Echoes in Simultaneous Image Refocusing
Inventors: Guenther, M.; D. A. Feinberg, D.A.                   
Filing date: 06/15/2002  
US 6853188

Efficient Visualization of Cortical Vascular Territories by Cycled Arterial Spin Labeling MRI
Inventors: Guenther, M.                                                   
Filing date: 05/20/2005                                                                                       

Extreme Speed-Up Of Acquisition Of Perfusion Time Series By Cycled Arterial Spin Labeling MRI
Inventors: Guenther, M.                                                   
Filing date: 09/19/2006                                                                                       

3D motion detection and correction by object tracking in ultrasound images
Inventors: Guenther, M., Bongers, A.                                
Filing date: 6/29/2009              
WO 2010037436 A1

Verfahren und Vorrichtung zur Ermittlung von T2 und T2* mittels MRT
Inventors: Guenther, M., Gregori, J.                                  
Filing date: 04/02/2009                                                                                       
WO2010112215 A1

Ultraschall-Messeinrichtung, Untersuchungsgerät und Verfahren zu deren Betrieb
Inventors: Tretbar, S; Degel, C; Günther, M                       
Filing date: 12/5/2012                                                                                       

ASL MRI using a sequence of magnetically labeled or unlabeled fluid boli
Inventors: von Samson-Himmelstjerna, F.; Günther, M       
Filing date: 03/27/2014             
WO 2015144768 A1

Imaging system for generating a series of image
Inventors: Braeutigam, N; von Samson-Himmelstjerna, F.; Günther, M,                                                                                     
Filing date: 4/20/2016,                                                                                       

System, method and computer program for magnetic resonance scanners: Calculation flow
Inventors: Cordes, C.; Porter, D.; Archipovas, S.; Günther, M.
Filing date: 4/20/2016,                                                                                      

Rekonstruktion von Ultraschalldaten mittels neuronaler Netzwerke    
Inventor: Günther, M.                                                     
Filing date: 11/09/2017                                                                                      

Magnetic resonance imaging system                                             
Inventor: Günther, M.                                                     
Filing date: 05/03/2018  
DE 10 2018 110 826.5

Cable Mantle/Jacket for shield current suppression
Inventor: Betancourt, D; Bertuch, T; Jenne,J; Günther, M.  
Filing date: 11/29/2019     


Reviewer for

(selection, since 2001):

European Commission, COST organization, European Research Council, Deutsche Forschungsgemeinschaft (DFG), Schweizer Nationalfond (SNF), Alexander von Humboldt-Stiftung, Deutscher Akademischer Auslandsdienst (DAAD),Research Promotion Foundation (RPF) of Cyprus, Poland - National Centre for Research and Development

Magnetic Resonance in Medicine, IEEE Transaction for Medical Imaging, Cerebrovascular Diseases, Journal of Magnetic Resonance Imaging, Journal of Neuroscience Methods, Journal of Neuroimaging, Journal of Neurology, Neurosurgery & Psychiatry, Kidney International, Zeitschrift für Medizinische Physik, Magnetic Resonance Materials in Physics Biology and Medicine, NeuroImage, Neuroradiodiology, Biomedical Signal Processing and Control, Applied Sciences, IPMI, MICCAI, ISMRM, ESMRMB