Neuroimaging Software Solutions

Our research and software development focus on monitoring neurological diseases, planning neurosurgical interventions, supporting clinical trials and performing quantitative studies.
Efficiency, reliability and accuracy of software assistants for evaluating neuroimaging data is of paramount importance within clinical settings, where planning results or therapy decisions might depend on individual measurements.
Diseases like brain tumors, arteriovenous malformations, multiple sclerosis or Alzheimer are only a small subset where our qualitative and quantitative neuroimaging techniques have already proven useful.


Neurological Monitoring

We provide advanced image analysis techniques required for a variety of neurological questions: fiber tracking, quantification of diffusion MRI data, volumetric brain analysis, ventricle volumetry, cortical thickness measurement, lesion segmentation and analysis of lesion correspondence.

Neurosurgical planning

Neurosurgical intervention planning demands for a precise and efficient reconstruction and visualization of the tumor and the risk structures like vessels, axonal fibers and functional areas. Based on multimodal MRI data we developed solutions for computing risk structures by fiber tracking, fMRI visualization and multi-modal vessel extraction.

Diffusion MRI

We provide solutions for efficient fiber tracking, clustering, uncertainty analysis, and fiber visualizations. While our algorithms can also rely on clinically established diffusion models like tensors, our fiber tracking algorithms are still able to reconstruct difficult constellations like fiber crossings.


  • Eurographics medical prize [1] and Eurographics Dirk Bartz prize [2] for neurosurgical software demonstrators.
  • Our application suite NeuroQLab has been ranked as the best tool in a clinical study, where the accuracy of nine different tractography algorithms has been examined [3].
  • Outstanding results at the MICCAI Tractography Challenge 2013, 2014 and 2015 have been achieved [4].
  • Fraunhofer MEVIS contributes in EU projects in the area of neuroimaging [5-7]


[1] A. Köhn et al., 1st Prize of EG Medical Prize 2007.
[2] F. Weiler et al., 3rd Dirk Bartz Prize EG 2011.
[3] G. Feigl et al., World Neurosurgery, 10.1016/j.wneu.2013.01.004.
[4] J. Klein et al., MICCAI 2013, 2014, 2015 - DTI Tractography Challenge.
[5] Wake-Up