Dr.-Ing. André Homeyer

  • Key Scientist Computational Pathology
  • Principal Data Scientist



Fedorov A, Longabaugh WJR, Pot D, Clunie DA, Pieper SD, Gibbs DL, Bridge C, Herrmann MD, Homeyer A, Lewis R, Aerts HJWL, Krishnaswamy D, Thiriveedhi VK, Ciausu C, Schacherer DP, Bontempi D, Pihl T, Wagner U, Farahani K, Kim E, Kikinis R (2023) National Cancer Institute Imaging Data Commons: Toward Transparency, Reproducibility, and Scalability in Imaging Artificial Intelligence. RadioGraphics 43(12):e230180
Jansen C, Lindequist B, Strohmenger K, Romberg D, Küster T, Weiss N, Franz M, Schwen LO, Evans T, Homeyer A, Zerbe N (2023) The vendor-agnostic EMPAIA platform for integrating AI applications into digital pathology infrastructures. Future Generation Computer Systems 140:209–224
Schacherer DP, Herrmann MD, Clunie DA, Höfener H, Clifford W, Longabaugh WJR, Pieper S, Kikinis R, Fedorov A, Homeyer A (2023) The NCI Imaging Data Commons as a platform for reproducible research in computational pathology. Computer Methods and Programs in Biomedicine 242:107839
Schwen LO, Kiehl TR, Carvalho R, Zerbe N, Homeyer A (2023) Digitization of Pathology Labs: A Review of Lessons Learned. Lab Invest 103(11):100244


Homeyer A, Geißler C, Schwen LO, Zakrzewski F, Evans T, Strohmenger K, Westphal M, Bülow RD, Kargl M, Karjauv A, Munné-Bertran I, Retzlaff CO, Romero-López A, Sołtysiński T, Plass M, Carvalho R, Steinbach P, Lan YC, Bouteldja N, Haber D, Rojas-Carulla M, Vafaei Sadr A, Kraft M, Krüger D, Fick R, Lang T, Boor P, Müller H, Hufnagl P, Zerbe N (2022) Recommendations on compiling test datasets for evaluating artificial intelligence solutions in pathology. Mod Pathol 35:1759–1769
Jansen C, Strohmenger K, Romberg D, Küster T, Weiss N, Lindequist B, Franz M, Homeyer A, Zerbe N (2022) The EMPAIA Platform: Vendor-neutral integration of AI applications into digital pathology infrastructures. Proceedings of the 22nd IEEE International Symposium on Cluster, Cloud and Internet Computing (CCGrid). IEEE, pp 1017–1027
Romberg D, Strohmenger K, Jansen C, Küster T, Weiss N, Geißler C, Sołtysiński T, Takla M, Hufnagl P, Zerbe N, Homeyer A (2022) EMPAIA App Interface: An open and vendor-neutral interface for AI applications in pathology. Comput Methods Programs Biomed 215:106596
Schwen LO, Schacherer D, Geißler C, Homeyer A (2022) Evaluating generic AutoML tools for computational pathology. Inform Med Unlocked 29:100853


Fedorov A, Longabaugh WJR, Pot D, Clunie DA, Pieper S, Aerts HJWL, Homeyer A, Lewis R, Akbarzadeh A, Bontempi D, Clifford W, Herrmann MD, Hofener H, Octaviano I, Osborne C, Paquette S, Petts J, Punzo D, Reyes M, Schacherer DP, Tian M, White G, Ziegler E, Shmulevich I, Pihl T, Wagner U, Farahani K, Kikinis R (2021) NCI Imaging Data Commons. Cancer Res 81(16):4188–4193
Homeyer A, Lotz J, Schwen LO, Weiss N, Romberg D, Höfener H, Zerbe N, Hufnagl P (2021) Artificial intelligence in pathology: From prototype to product. J Pathol Inform 12(1):13
Hua C, Wei W, Zhang T, Xu F, Dirsch O, Homeyer A, Settmacher U, Dahmen U (2021) Additional partial hepatectomy at the time of portal vein ligation accelerates the regeneration of the future liver remnant. Sci Rep 11(1):11740


Wei W, Hua C, Zhang T, Dirsch O, Gremse F, Homeyer A, Settmacher U, Dahmen U (2020) Size of portally deprived liver lobe after portal vein ligation and additional partial hepatectomy: Result of balancing proliferation and apoptosis. Sci Rep 10:4893


Höfener H, Homeyer A, Förster M, Drieschner N, Schildhaus H-U, Hahn HK (2019) Automated Density-based Counting of FISH Amplification Signals for HER2 Status Assessment. Comput Methods Programs Biomed 173:77–85
Homeyer A (2019) Automated analysis of necrosis and steatosis in histological images : Practical solutions for coping with heterogeneity and variability. Ph.D. thesis


Höfener H, Homeyer A, Weiss N, Molin J, Lundström CF, Hahn HK (2018) Deep learning nuclei detection: A simple approach can deliver state-of-the-art results. Comput Med Imaging Graph 70:43–52
Homeyer A, Hammad S, Schwen LO, Dahmen U, Höfener H, Gao Y, Dooley S, Schenk A (2018) Focused scores enable reliable discrimination of small differences in steatosis. Diagn Pathol 13(76):1–9
Schwen LO, Andersson A, Korski K, Weiss N, Haase S, Gaire F, Hahn HK, Homeyer A, Grimm O (2018) Data-Driven Discovery of Immune Contexture Biomarkers. Front Oncol 8(627):1–15
Weiss N, Kost H, Homeyer A (2018) Towards Interactive Breast Tumor Classification Using Transfer Learning. In: Campilho A, Karray F, ter Haar Romeny B (eds) Proceeding of International Conference Image Analysis and Recognition. LNCS 10882, pp 727–736


Arlt J, Wei W, Xie C, Homeyer A, Settmacher U, Dahmen U, Dirsch O (2017) Modulation of hepatic perfusion did not improve recovery from hepatic outflow obstruction. BMC Pharmacol Toxicol 18(1)
Homeyer A, Nasr P, Engel C, Kechagias S, Lundberg P, Ekstedt M, Kost H, Weiss N, Palmer T, Hahn HK, Treanor D, Lundström C (2017) Automated quantification of steatosis: agreement with stereological point counting. Diagn Pathol 12(1):80
Kost H, Homeyer A, Molin J, Lundström C, Hahn HK (2017) Training nuclei detection algorithms with simple annotations. J Pathol Inform 8(1):1–9


Arlt J, Homeyer A, Sänger C, Dahmen U, Dirsch O (2016) One Size Fits All: Evaluation of the Transferability of a New “Learning” Histologic Image Analysis Application. Appl Immunohistochem Mol Morphol 24(1):1–10
Ehteshami Bejnordi B, Litjens G, Timofeeva N, Otte-Holler I, Homeyer A, Karssemeijer N, van der Laak J (2016) Stain specific standardization of whole-slide histopathological images. IEEE Trans Med Imaging 35(2):404–415
Kost H, Homeyer A, Bult P, Balkenhol MCA, van der Laak JAWM, Hahn HK (2016) A generic nuclei detection method for histopathological breast images. Proceedings of SPIE Medical Imaging: Digital Pathology. 97911E:pp 1–7
Schwen LO, Homeyer A, Schwier M, Dahmen U, Dirsch O, Schenk A, Kuepfer L, Preusser T, Schenk A (2016) Zonated quantification of steatosis in an entire mouse liver. Comput Biol Med 73:108–118
Wei W, Zhang T, Fang H, Dirsch O, Schenk A, Homeyer A, Gremse F, Zafarnia S, Settmacher U, Dahmen U (2016) Intrahepatic Size Regulation in a Surgical Model: Liver Resection-Induced Liver Regeneration Counteracts the Local Atrophy following Simultaneous Portal Vein Ligation. Eur Surg Res 57(1-2):125–137


Homeyer A, Schenk A, Arlt J, Dahmen U, Dirsch O, Hahn HK (2015) Fast and accurate identification of fat droplets in histological images. Comput Meth Prog Bio 121(2):59–65


Czigany Z, Turoczi Z, Kleiner D, Lotz G, Homeyer A, Harsanyi L, Szijarto A (2014) Neural elements behind the hepatoprotection of remote perconditioning. J Surg Res 193(2):642–651
Lotz J, Berger J, Müller B, Breuhahn K, Grabe N, Heldmann S, Homeyer A, Lahrmann B, Laue H, Olesch J, Schwier M, Sedlaczek O, Warth A (2014) Zooming in: High Resolution 3D Reconstruction of Differently Stained Histological Whole Slide Images. Proceeding of SPIE Medical Imaging: Digital Pathology. 904104:pp 1–7
Wang L, Harz M, Boehler T, Platel B, Homeyer A, Hahn HK (2014) A robust and extendable framework towards fully automated diagnosis of nonmass lesions in breast DCE-MRI. IEEE International Symposium on Biomedical Imaging. pp 129–132


Chitiboi T, Homeyer A, Linsen L, Hahn HK (2013) Object-Based Boundary Properties. Bildverarbeitung für die Medizin. Springer, pp 199–204
Deng M, Dirsch O, Sun J, Huang H, Sehestedt C, Homeyer A, Schenk A, Dahmen U (2013) Limited Correlation between Conventional Pathologist and Automatic Computer-assisted Quantification of Hepatic Steatosis due to Difference between Event-based and Surface-based Analysis. IEEE J Biomed Health Inform 18(4):1473–1477
Homeyer A, Schenk A, Arlt J, Dahmen U, Dirsch O, Hahn HK (2013) Practical quantification of necrosis in histological whole-slide images. Comput Med Imaging Graph 37(4):313–322


Homeyer A, Dahmen U, Huang H, Schenk A, Dirsch O, Hahn HK (2011) A comparison of sampling strategies for histological image analysis. J Pathol Inform 2(2):11
Ritter F, Boskamp T, Homeyer A, Laue H, Schwier M, Link F, Peitgen H-O (2011) Medical image analysis. IEEE Pulse 2(6):60–70


Hahn HK, Harz M, Seyffarth H, Zoehrer F, Boehler T, Filippatos K, Wang L, Homeyer A, Ritter F, Laue H, Guenther M, Twellmann T, Tabár L, Bick U, Schilling K (2010) Concepts for Efficient and Reliable Multi-Modal Breast Image Reading. 10th International Workshop on Digital Mammography (IWDM 2010). Springer, Girona, pp 121–128
Homeyer A, Schwier M, Hahn HK (2010) A Generic Concept for Object-Based Image Analysis. Proceedings of the International Conference on Computer Vision Theory and Applications. pp 530–533
Ivanovska T, Schenk A, Homeyer A, Deng M, Dahmen U, Dirsch O, Hahn HK, Linsen L (2010) A fast and robust hepatocyte quantification algorithm including vein processing. BMC Bioinformatics 11:124