All Publications From Prof. Dr. Tobias Preusser


Mirzaee H, Henn T, Krause MJ, Goubergrits L, Schumann C, Neugebauer M, Kuehne T, Preusser T, Hennemuth A (2017) MRI-based computational hemodynamics in patients with aortic coarctation using the lattice Boltzmann methods: Clinical validation study. J Magn Reson Imaging 45(1):139–146
Schwenke M, Georgii J, Preusser T (2017) Fast Numerical Simulation of Focused Ultrasound Treatments during Respiratory Motion with Discontinuous Motion Boundaries. IEEE Trans Biomed Eng 64(7):1455–1468
Schwenke M, Strehlow J, Demedts D, Haase S, Barrios Romero D, Rothlübbers S, von Dresky C, Zidowitz S, Georgii J, Mihcin S, Bezzi M, Tanner C, Sat G, Levy Y, Jenne J, Günther M, Melzer A, Preusser T (2017) A focused ultrasound treatment system for moving targets (part I): generic system design and in-silico first-stage evaluation. J Ther Ultrasound 5(1) doi:10.1186/s40349-017-0098-7


Lübke D, Georgii J, Schwenke M, v. Dresky C, Haller J, Günther M, Preusser T, Jenne JW (2016) Comparison of MR thermometry and HIFU simulations in a calibrated setup. Proc. of the 16th International Symposium on Therapeutic Ultrasound
Schwen LO, Homeyer A, Schwier M, Dahmen U, Dirsch O, Schenk A, Kuepfer L, Preusser T, Schenk A (2016) Zonated quantification of steatosis in an entire mouse liver. Comput Biol Med 73:108–118
Schwenke M., Strehlow J., Haase S., Tanner C., Rothlübbers S., Preusser T (2016) A real-time data processing framework for steered FUS. 5th International Symposium on Focused Ultrasound: North Bethesda, MD, USA. 28 August- 1 September 2016
Tanner C, Zur Y, French K, Samei G, Strehlow J, Sat G, McLeod H, Houston G, Kozerke S, Székely G, Melzer A, Preusser T (2016) In vivo validation of spatio-temporal liver motion prediction from motion tracked on MR thermometry images. Int J CARS 11(6):1143–1152


Rieder C, Ballhausen H, Poch F, Gemeinhard O, Lehmann K, Preusser T (2015) Ex Vivo Validation of a Numerical Simulation for Multipolar Radiofrequency Ablation. Proc. of CURAC 2015. pp 55–60
Schumann C, Rieder C, Haase S, Teichert K, Süss P, Isfort P, Bruners P, Preusser T (2015) Interactive multi-criteria planning for radiofrequency ablation. Int J CARS 10(6):879–889
Schwen LO, Pätz T, Preusser T (2015) Some Use Cases for Composite Finite Elements in Image Based Computing. In: Joldes GR, Doyle B, Wittek A, Nielsen PMF, Miller K (eds) MICCAI 2015 Workshop Proceedings Computational Biomechanics for Medicine X. pp 128–140
Schwen LO, Schenk A, Kreutz C, Timmer J, Bartolomé Rodriguez MM, Kuepfer L, Preusser T (2015) Representative Sinusoids for Hepatic Four-Scale Pharmacokinetics Simulations. PLoS ONE 10(7):e0133653
Schwen LO, Wei W, Gremse F, Ehling J, Wang L, Dahmen U, Preusser T (2015) Algorithmically Generated Rodent Hepatic Vascular Trees in Arbitrary Detail. J Theor Biol 365:289–300
Schwenke M, Strehlow J, Haase S, Jenne J, Tanner C, Langø T, Loeve AJ, Karakitsios I, Xiao X, Levy Y, Sat G, Bezzi M, Braunewell S, Guenther M, Melzer A, Preusser T (2015) An integrated model-based software for FUS in moving abdominal organs. Int J Hyperthermia 31(3):240–250
Strehlow J, Xiao X, Domschke M, Schwenke M, Karakitsios I, Mihcin S, Schwaab J, Levy Y, Preusser T, Melzer A (2015) US-tracked steered FUS in a respiratory ex vivo ovine liver phantom. Current Directions in Biomedical Engineering 1(1):294–297
Strehlow J, Xiao X, Schwenke M, Karakitsios I, Domschke M, Mihcin S, Levy Y, Preusser T, Melzer A (2015) Ultrasound tracked motion compensated focused ultrasound system evaluated on ex vivo ovine livers. Journal of Therapeutic Ultrasound. 52


Acharya D, Georgii J, Preusser T (2014) Towards multi-criteria optimization of transducer configurations. Focused Ultrasound 2014, 4th International Symposium
Pätz T, Preusser T (2014) Segmentation of Stochastic Images using Level Set Propagation with Uncertain Speed. J Math Imaging Vis 48(3):467–487
Ristovski G, Preusser T, Hahn HK, Linsen L (2014) Uncertainty in medical visualization: Towards a taxonomy. Comput Graph 39:60–73
Schumann C, Muecke E, Demedts D, Georgii J, von Dresky C, Preusser T (2014) Interactive Approximation of High-Intensity Focused Ultrasound Simulation for Arbitrary Transducer Configurations. Proc. of Society of Thermal Medicine. 114
Schumann C, Demedts D, Georgii J, von Dresky C, Preusser T (2014) Computer Assisted Planning of High Intensity Focused Ultrasound Treatment of the Liver. Proc. of Image-Guided Interventions (IGIC). pp 33–34
Schwen LO, Krauss M, Niederalt C, Gremse F, Kiessling F, Schenk A, Preusser T, Kuepfer L (2014) Spatio-Temporal Simulation of First Pass Drug Perfusion in the Liver. PLoS Comput Biol 10(3):e1003499


Demedts D, Schumann C, Georgii J, von Dresky C, Preusser T (2013) Hardware-independent pre-interventional planning, simulation, and application of focused ultrasound therapy. 13th International Symposium for Therapeutic Ultrasound. Shanghai, 51
Georgii J, Borasi G, Russo G, Candiano GC, Gilardi MC, Alongi F, Messa C, Preusser T (2013) Integration of Focused Ultrasound with Radiotherapy: the benefit of the hyperthermia field. FUS Therapy Symposium
Georgii J, Demedts D, Schumann C, von Dresky C, Preusser T (2013) Computergestützte Planung von Tumortherapien mit hoch-intensivem fokussiertem Ultraschall. Treffpunkt Medizintechnik
Georgii J, v. Dresky C, Meier S, Schumann S, Demedts D, Preusser T (2013) Simulation of HIFU treatments with efficient numerical techniques. Proc. of Society of Thermal Medicine
Georgii J, von Dresky C, Demedts D, Schumann C, Preusser T (2013) Planning of HIFU therapies of moving organs by using numerical simulation techniques. FUS Therapy Symposium
Meier S, Hennemuth A, Drexl J, Bock J, Jung B, Preusser T (2013) A fast and noise-robust method for computation of intravascular pressure difference maps from 4D PC-MRI data. In: Camara O, Konukoglu E, Pop M, Rhode K, Sermesant M, Young A (eds) Statistical Atlases and Computational Models of the Heart. LNCS, pp 215–224
Mirzaee H, Meier S, Hennemuth A, Preusser T, Harloff A (2013) Patient-specific mesoscopic blood flow simulation: From image data to flow analysis. Proc. of Modelling of Physiological Flows. Sardinia, 31
Schumann C, Rieder C, Haase S, Preusser T (2013) Interactive Access Path Exploration for Planning of Needle-Based Interventions. Deutsche Gesellschaft für Computer- und Roboterassistierte Chirurgie. pp 103–106


Altrogge I, Büskens C, Kröger T, Peitgen H-O, Preusser T, Tiesler H (2012) Modeling, Simulation and Optimization of Radio Frequency Ablation. Constrained Optimization and Optimal Control for Partial Differential Equations 487–499
Altrogge I, Preusser T, Kröger T, Haase S, Pätz T, Kirby RM (2012) Sensitivity Analysis for the Optimization of Radiofrequency Ablation in the Presence of Material Parameter Uncertainty. International Journal for Uncertainty Quantification 2(3):295–321
Braunewell S, Günther M, Preusser T (2012) Towards Focused Ultrasound Liver Surgery under Free Breathing. Critical Reviews in Biomedical Engineering 40(3):221–234
Haase S, Süss P, Schwientek J, Teichert K, Preusser T (2012) Radiofrequency ablation planning: An application of semi-infinite modelling techniques. Eur J Oper Res 218(3):856–864
Haase S, Pätz T, Tiesler H, Altrogge I, Preusser T (2012) Radiofrequency ablation planning beyond simulation. Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE. pp 191–194
Jenne JW, Preusser T, Günther M (2012) High-intensity focused ultrasound: Principles, therapy guidance, simulations and applications. Z Med Phys 22(4):311–322
Pätz T, Preusser T (2012) Composite Finite Elements for a Phase-Change Model. SIAM Journal on Scientific Computing 34(5):B672–B691
Pätz T, Preusser T (2012) Fast Parameter Sensitivity Analysis of PDE-Based Image Processing Methods. ECCV 2012, Part VII, LNCS. pp 140–153
Pätz T, Preusser T (2012) Segmentation of Stochastic Images with a Stochastic Random Walker Method. IEEE Trans Image Process 21(5):2424–2433
Pätz T, Kirby RM, Preusser T (2012) Ambrosio-Tortorelli Segmentation of Stochastic Images: Model Extensions, Theoretical Investigations and Numerical Methods. International Journal of Computer Vision e-pub
Rieder C, Poch F, Tiesler H, Lehmann K, Preusser T (2012) Software Tool for the Analysis of the Coagulation Zone from Multipolar Radiofrequency Ablation. Proceedings of CURAC. pp 193–196
Schwen LO, Preusser T (2012) Analysis and Algorithmic Generation of Hepatic Vascular Systems. International Journal of Hepatology 2012(Article ID 357687):1–17
Schwen LO, Pätz T, Preusser T (2012) Composite Finite Element Simulation of Radio Frequency Ablation and Bone Elasticity. In: Eberhardsteiner J, et al (eds) Proceedings of the 6th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS2012)
Tiesler H, Haase S, Schwenke M, Bieberstein J, Preusser T (2012) Software Assistance for HIFU Therapy Planning. Biomedizinische Technik. Biomedical Engineering
Tiesler H, Kirby RM, Xiu D, Preusser T (2012) Stochastic Collocation for Optimal Control Problems with Stochastic PDE Constraints. SIAM J Control Optim 50(5):2659–2682


Georgii J, v. Dresky C, Meier S, Demedts D, Schumann C, Preusser T (2011) Focused Ultrasound – Efficient GPU Simulation Methods for Therapy Planning. Proc. of Workshop on Virtual Reality Interaction and Physical Simulation (VRIPHYS). pp 119–128
Pätz T, Preusser T (2011) Simulation of water evaporation during radiofrequency ablation using composite finite elements. The International Journal of Multiphysics, Special Edition: Multiphysics Simulations – Advanced Methods for Industrial Engineering 145–156
Pätz T, Kirby RM, Preusser T (2011) Segmentation of Stochastic Images using Stochastic Extensions of the Ambrosio-Tortorelli and the Random Walker Model. Proceedings in Applied Mathematics and Mechanics. pp 859–860
Preusser T, Rumpf M, Sauter S, Schwen LO (2011) 3D composite finite elements for elliptic boundary value problems with discontinuous coefficients. SIAM J Sci Comput 33(5):2115–2143
Schenk A, Haemmerich D, Preusser T (2011) Planning of Image-Guided Interventions in the Liver. IEEE Pulse 2(5):48–55


Eslami A, Jahed M, Preusser T (2010) Joint Edge Detection and Motion Estimation of Cardiac MR Image Sequences by a Phase Field Method. Comp Biol Med 40(1):21–28
Georg M, Preusser T, Hahn HK (2010) Global Constructive Optimization of Vascular Systems. Department of Computer Science & Engineering - Washington University, St. Louis, 1–13
Kröger T, Pannier S, Kaliske M, Altrogge I, Graf W, Preusser T (2010) Optimal applicator placement in hepatic radiofrequency ablation on the basis of rare data. Comput Meth Biomech Biomed Eng 13(3):431–440
Kröger T, Pätz T, Altrogge I, Schenk A, Lehmann KS, Frericks BB, Ritz JP, Peitgen HO Preusser T (2010) Fast Estimation of the Vascular Cooling in RFA Based on Numerical Simulation. Open Biomed Eng J 4:16–26
Meier S, Hennemuth A, Friman O, Bock J, Markl M, Preusser T (2010) Noninvasive 4D Blood Flow and Pressure Quantification in Central Blood Vessels via PCMRI. Proc. IEEE Computing in Cardiology. pp 903–906
Pätz T, Preusser T (2010) Ambrosio-Tortorelli Segmentation of Stochastic Images. In: Daniilidis K and M Petros and Paragios Nikos (ed) Computer Vision – ECCV 2010. Lecture Notes in Computer Science, pp 254–267
Preusser T, Peitgen H-O (2010) Patient-Specific Planning for Radio-Frequency Ablation of Tumors in the Presence of Uncertainty. it – Information Technology 52(5):265–271
Rieder C, Altrogge I, Kröger T, Zidowitz S, Preusser T (2010) Interactive Approximation of the Ablation Zone incorporating Heatsink Effects for Radiofrequency Ablation. Proceedings of CURAC. pp 9–12
Schumann C, Rieder C, Bieberstein J, Weihusen A, Zidowitz S, Moltz JH, Preusser T (2010) State of the Art in Computer-Assisted Planning, Intervention and Assessment of Liver Tumor Ablation. Critical Reviews in Biomedical Engineering 38(1):31–52
Weihusen A, Hinrichsen L, Carus T, Dammer R, Rascher-Friesenhausen R, Kröger T, Peitgen H-O, Preusser T (2010) Towards a verified simulation model for radiofrequency ablations. Proceedings IPCAI. pp 179–189
Zidowitz S, Altrogge I, Hansen C, Hindennach M, Kröger T, Ojdanic D, Rieder C, Preusser T, Schenk A, Weihusen A, Wirtz S, Prause G, Peitgen H-O (2010) Computer-Assisted Risk Prevention in Surgical and Interventional Treatment of Liver Tumor. Zeitschrift für Biomedizinische Technik. BMT, pp 74–77


Altrogge I, Pätz T, Kröger T, Peitgen H-O, Preusser T (2009) Optimization & Fast Estimation of Vessel Cooling for RF Ablation. International Federation for Medical and Biological Engineering. Springer, Berlin / Heidelberg, pp 1202–1205
Liehr F, Preusser T, Rumpf M, Sauter S, Schwen LO (2009) Composite finite elements for 3D image based computing. Comput Vis Sci 12(4):171–188
Pätz T, Kröger T, Preusser T (2009) Simulation of Radiofrequency Ablation including Water Evaporation. IFMBE Proceedings 25(4):1287–1290
Schwen LO, Preusser T, Rumpf M (2009) Composite Finite Elements for 3D Elasticity with Discontinuous Coefficients. Proceedings of the 16th Workshop on the Finite Element Method in Biomedical Engineering, Biomechanics and Related Fields


Kröger T, Preusser T (2008) Stability of the 8-tetrahedra Shortest-Interior-Edge Partitioning Method. Numer Math 109(3):435–457
Kröger T, Altrogge I, Konrad O, Kirby RM, Preusser T (2008) Estimation of Probability Density Functions for Parameters Sensitivity Analyses. In: Hauser H, Strassburger S, Theisel H (eds) Proceedings of SimVis. Magdeburg, pp 61–74
Preusser T, Scharr H, Krajsek K, Kirby RM (2008) Building blocks for image processing with stochastic partial differential equations. Int J Comput Vis 80:375–405


Altrogge I, Preusser T, Kröger T, Büskens C, Pereira PL, Schmidt D, Peitgen H-O (2007) Multi-Scale Optimization of the Probe Placement for Radio-Frequency Ablation. Acad Radiol 14(11):1310–1324
Gasteiger R, Ritter F, Preim B, Preusser T (2007) Visualisierung von Simulationsparametern thermischer Tumorablationsverfahren. Simulation und Visualisierung. pp 325–340
Preusser T (2007) Viscosity solutions of a level-set method for anisotropic geometric diffusion in image processing. J Math Imaging Vis 29(2-3):205–217
Preusser T, Droske M, Garbe C, Rumpf M, Telea A (2007) A phase-field method for joint denoising, edge detection, and motion estimation in image sequence processing. SIAM J Appl Math 68(3):599–618
Weihusen A, Ritter F, Kröger T, Preusser T, Zidowitz S, Peitgen H-O (2007) Workflow oriented software support for image guided radiofrequency ablation of focal liver malignancies. In: Cleary KR, Miga MI (eds) Proceedings of SPIE Medical Imaging. SPIE Press, San Diego, California, USA, 650919:pp 1–9
Zidowitz S, Drexl H, Kröger T, Preusser T, Ritter F, Weihusen A, Peitgen H-O (2007) Baysian Vessel Extraction for Planning of RF-Ablation. In: Horsch A, Deserno TM, Handels H, Meinzer H-P, Tolxdorff T (eds) Bildverarbeitung für die Medizin. pp 187–191


Altrogge I, Kröger T, Preusser T, Büskens C, Pereira P, Schmidt D, Weihusen A, Peitgen H-O (2006) Towards Optimization of Probe Placement for Radio-Frequency Ablation. In: Larsen R, Nielsen M, Sporring J (eds) Proceedings of MICCAI. Proc. MICCAI, Lect. Not. Comp. Sci. 4190, pp 486–493
Kröger T, Altrogge I, Preusser T, Pereira P, Schmidt D, Weihusen A, Peitgen H-O (2006) Numerical simulation of radio frequency ablation with state dependent material parameters in three space dimensions. In: Larsen R, Nielsen M, Sporring J (eds) Medical Image Computing and Computer-Assisted Intervention. Proc. MICCAI, Lect. Notes Comp. Sci. 4191, pp 380–388
Preusser T, Telea A, Garbe C, Droske M, Rumpf M (2006) A variational approach to Joint Denoising, Edge detection and motion estimation. Pattern Recognition. Proceedings of DAGM, pp 525–553


Preusser T, Weihusen A, Peitgen H-O (2005) On the modelling of perfusion in the simulation of RF-ablation. In: Schulze T, Horton G, Preim B, Schlechtweg S (eds) Simulation and Visualization. SCS-Verlag, Ghent, pp 259–269


Preusser T, Liehr F, Rumpf M, Sauter U, Weikard U, Peitgen H-O (2004) Simulation of Radio-Frequency Ablation using Composite Finite Element Methods. Perspective in Image Guided Surgery, Proceedings of the Scientific Workshop on Medical Robotics, Navigation and Visualization. World Scientific, Hackensack, pp 303–310