Prof. Dr.-Ing. Horst K. Hahn

  • Institute Director
  • Professor for Medical Imaging at Jacobs University Bremen


Horst Hahn studied physics with the minors mathematics, computer science, and physiology at the University of Bayreuth, Paul Sabatier University Toulouse, and Heidelberg University, and is the author of 6 patents and over 250 peer reviewed scientific papers and book chapters in the field of computer-assisted medicine. In 2006, he became a deputy director of the non-profit MeVis Research GmbH and was involved in a central role in their transformation into the Fraunhofer Institute for Medical Image Computing (MEVIS) on January 1, 2009, for which he acted as a director since April 2012. He was appointed director of Fraunhofer MEVIS in May 2014 jointly with Ron Kikinis. At the age of 35, he was appointed Adjunct Professor of Medical Visualization and four years later Professor of Medical Imaging at Jacobs University Bremen. In January 2012, he was visiting professor at the Diagnostic Image Analysis Group at Radboud University Medical Center in Nijmegen.
 
He was a scientific coordinator of several national and European collaborative projects, including HAMAM (Highly Accurate Breast Cancer Diagnosis through Integration of Biological Knowledge, Novel Imaging Modalities, and Modelling, EC FP7, 2008-2012) and VPH-PRISM (Virtual Physiological Human: Personalised Predictive Breast Cancer Therapy Through Integrated Tissue Micro-Structure Modeling, EC FP7, 2013-2016), which he initiated. He has received numerous prizes and awards, and finished his PhD summa cum laude in the field of quantitative medical imaging at the University of Bremen, for which he received the Bruker Daltonik special award as part of the Bremen Study Prize. In July 2011, he organized the International Conference on Information Processing in Medical Imaging together with Gábor Székely for the first time in Germany, and within the 2014 Science Year he was selected as one of Germany's Digital Heads.
 
His scientific and technological work addresses the digital transformation of medicine on the basis of multidisciplinary data integration and modern machine learning methods. The consistent focus on quantification, consistency, and automation in medical imaging as well as the best possible use of all available information form the basis for a new generation of clinical decision support systems and predictive tools for an improved early detection, differential diagnosis, and therapy optimization of cancer and neurological diseases.
In face of the rapidly advancing specialization of modern medicine with ever-increasing amounts of data and at the same time increasing cost pressure in the overall health system, his research aims at a sustained increase in efficiency and at the same time raising the quality and safety of both diagnostic and therapeutic processes.
 

Publications

2018

Black D, Hahn HK, Kikinis R, Wardell K, Haj-Hosseini N (2018) Auditory display for fluorescence-guided open brain tumor surgery. Int J CARS 13(1):25–35
Black D, Unger M, Fischer N, Kikinis R, Hahn H, Neumuth T, Glaser B (2018) Auditory display as feedback for a novel eye-tracking system for sterile operating room interaction. Int J CARS 13(1):37–45
Chlebus G, Schenk A, Moltz JH, van Ginneken B, Hahn HK, Meine H (2018) Automatic liver tumor segmentation in CT with fully convolutional neural networks and object-based postprocessing. Scientific Reports 8
Haensch A, Dicken V, Gass T, Morgas T, Klein J, Meine H, Hahn HK (2018) Deep learning based segmentation of organs of the female pelvis in CBCT scans for adaptive radiotherapy using CT and CBCT data. International Journal of Computer Assisted Radiology and Surgery. pp 179–180
Hahn H, Schreiber A (2018) E-Health: Potenziale der Digitalen Transformation in der Medizin. In: Neugebauer R (ed) Digitalisierung. Springer Vieweg, Berlin, Heidelberg, pp 321–345
Hänsch A, Gass T, Morgas T, Haas B, Meine H, Klein J, Hahn HK (2018) Parotid gland segmentation with deep learning using clinical vs. curated training data. Radiotherapy and Oncology. 278
Hänsch A, Schwier M, Gass T, Morgas T, Haas B, Dicken V, Meine H, Klein J, Hahn HK (2018) Evaluation of deep learning methods for parotid gland segmentation from CT images. Journal of Medical Imaging 6(1):011005
Hänsch A, Schwier M, Gass T, Morgasz T, Haas B, Klein J, Hahn HK (2018) Comparison of different deep learning approaches for parotid gland segmentation from CT images. Proceedings of SPIE Medical Imaging 2018: Computer-Aided Diagnosis. 1057519:pp 1–6
Höfener H, Homeyer A, Weiss N, Molin J, Lundström CF, Hahn HK (2018) Deep learning nuclei detection: A simple approach can deliver state-of-the-art results. Comput Med Imaging Graph 70(C):43–52
Liu Y, Duan Y, Huang J, Ren Z, Liu Z, Dong H, Weiler F, Hahn HK, Shi F-D, Butzkueven H, Barkhof F, Li K (2018) Different patterns of longitudinal brain and spinal cord changes and their associations with disability progression in NMO and MS. Eur Radiol 28(1):96–103

2017

Al-Taie A, Hahn HK, Linsen L (2017) Combining rules using local statistics and uncertainty estimates for improved ensemble segmentation. Pattern Recognit Image Anal 27(3):444–457
Black D, Hansen C, Nabavi A, Kikinis R, Hahn H (2017) A Survey of auditory display in image-guided interventions. Int J CARS 12(10):1665–1676
Black D, Hettig J, Luz M, Hansen C, Kikinis R, Hahn H (2017) Auditory feedback to support image-guided medical needle placement. Int J CARS 12(9):1655–1663
Haensch A, Harz M, Schenk A, Endo I, Jacobs C, Hahn HK, Meine H (2017) Examining the robustness of liver segmentation using deep learning and unsupervised pre-training of a feature extractor. International Journal of Computer Assisted Radiology and Surgery. Springer International Publishing, pp 23–24
Homeyer A, Nasr P, Engel C, Kechagias S, Lundberg P, Ekstedt M, Kost H, Weiss N, Palmer T, Hahn HK, Treanor D, Lundström C (2017) Automated quantification of steatosis: agreement with stereological point counting. Diagn Pathol 12(1)
Kost H, Homeyer A, Molin J, Lundström C, Hahn HK (2017) Training nuclei detection algorithms with simple annotations. J Pathol Inform 8(1):1–9
Ristovski G, Matute J, Wehrum T, Harloff A, Hahn HK, Linsen L (2017) Uncertainty visualization for interactive assessment of stenotic regions in vascular structures. Comput Graph 69:116–130
Schneider R, Bellenberg B, Kleiter I, Gold R, Koster O, Weiler F, Hahn H, Lukas C (2017) Cervical cord and ventricle affection in neuromyelitis optica. Acta Neurol Scand 135(3):324–331
Schulz-Wendtland R, Harz M, Meier-Meitinger M, Brehm B, Wacker T, Hahn HK, Wagner F, Wittenberg T, Beckmann MW, Uder M, Fasching PA, Emons J (2017) Semi-Automated Delineation of Breast Cancer Tumors and Subsequent Materialization Using Three-Dimensional Printing (Rapid Prototyping). J Surg Oncol 115(3):238–242
Zoehrer F, Huellebrand M, Chitiboi T, Oechtering T, Sieren M, Frahm J, Hahn HK, Hennemuth A (2017) Real-time myocardium segmentation for the assessment of cardiac function variation. In: Andrzej Krol, Barjor Gimi (eds) SPIE Medical Imaging. 101370L:pp 1–7

2016

Chitiboi T, Schnell S, Collins J, Carr J, Chowdhary V, Honarmand AR, Hennemuth A, Linsen L, Hahn HK, Markl M (2016) Analyzing myocardial torsion based on tissue phase mapping cardiovascular magnetic resonance. J Cardiovasc Magn Reson 18(1):15
Chitiboi T, Hennemuth A, Schnell S, Varun Chowdhary V, Honarmand A, Markl M, Linsen L Hahn H (2016) Contour tracking and probabilistic segmentation of tissue phase mapping MRI. Proc. SPIE Medical Imaging: Image Processing. 978404:pp 1–8
Georgii J, Pätz T, Harz M, Stöcker C, Rothgang M, Colletta J, Schilling K, Schlooz-Vries M, Mann RM, Hahn HK (2016) Simulation and Visualization to support Breast Surgery Planning. Proc. of 13th International Workshop on Breast Imaging. pp 257–264
Kohlmann P, Boskamp T, Köhn A, Rieder C, Schenk A, Link F, Siems U, Barann M, Kuhnigk J-M, Demedts D, Hahn HK (2016) Remote Visualization Techniques for Medical Imaging Research and Image-Guided Procedures. Visualization in Medicine and Life Sciences III. Springer, pp 133–154
Kost H, Homeyer A, Bult P, Balkenhol MCA, van der Laak JAWM, Hahn HK (2016) A generic nuclei detection method for histopathological breast images. In: Gurcan MN, Madabhushi A (eds) Proc. SPIE Medical Imaging: Digital Pathology. 97911E:pp 1–7
Liu Y, Lukas C, Steenwijk MD, Daams M, Versteeg A, Duan Y, Li K, Weiler F, Hahn HK, Wattjes MP, Barkhof F, Vrenken H (2016) Multicenter Validation of Mean Upper Cervical Cord Area Measurements from Head 3D T1-Weighted MR Imaging in Patients with Multiple Sclerosis. AJNR Am J Neuroradiol 37(4):749–754
Schwier M, Hahn HK, Dahmen U, Dirsch O (2016) Segmentation of vessel structures in serial whole slide sections using region-based context features. Proc. SPIE Medical Imaging: Digital Pathology. 97910E:pp 1–14
Wang L, Schnurr A-K, Zidowitz S, Georgii J, Zhao Y, Razavi M, Schwier M, Hahn HK, Hansen C (2016) Segmentation of hepatic artery in multi-phase liver CT using directional dilation and connectivity analysis. Proc. SPIE Medical Imaging: Computer-Aided Diagnosis. 97851P:pp 1–8
Wang L, Chitiboi T, Meine H, Günther M, Hahn HK (2016) Principles and methods for automatic and semi-automatic tissue segmentation in MRI data. Magn Reson Mater Phy 29(2):95–110
Weiler F, Chlebus G, Brachmann C, Traulsen N, Waring A, Rieder C, Lassen-Schmidt B, Krass S, Hahn H (2016) A Modular Analysis Tool for Imaging-Based Clinical Research in Radiation Therapy. International Journal of Radiation Oncology*Biology*Physics. pp E418–E419

2015

Chitiboi T, Hennemuth A, Tautz L, Huellebrand M, Frahm J, Hahn HK (2015) Automatic multi-cycle analysis of cardiac function from real-time MRI. Proc. of 18th Annual SCMR Scientific Sessions. P 385
Chitiboi T, Schnell S, Collins J, Carr J, Hahn H, Markl M (2015) Analyzing Myocardial Torsion based on Tissue Phase Mapping MRI. Proceedings of the 23rd Annual Meeting ISMRM. 2722
Hahn HK, Kikinis R, Klein J, Nabavi A, Weber S (2015) 14. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie, CURAC 2015. ISBN 978–3-00–050359-7
Homeyer A, Schenk A, Arlt J, Dahmen U, Dirsch O, Hahn HK (2015) Fast and accurate identification of fat droplets in histological images. Comput Meth Prog Bio 121(2):59–65
Ivanovska T, Wang L, Gloger O, Hahn H, Völzke H, Hegenscheid K (2015) Sliding Level Set-Based Boundary: Fully Automated Dense Breast Segmentation in Native MR Mammograms. Proc. 3rd MICCAI Workshop on Breast Image Analysis. pp 57–64
Klein J, Geisler B, Hahn HK (2015) NeuroQLab DTI – Probabilistic Parameter Adaption for Effcient Fiber Tracking. Proc. of MICCAI 2015 – DTI Tractography Challenge
Klein J, Hanken K, Koceva J, Hildebrandt H, Hahn HK (2015) Measuring the lesion load of multiple sclerosis patients within the corticospinal tract. Proc. of SPIE Medical Imaging: Image Processing. 94130A:pp 1–7
Laue H, Lotz J, Kohlmann P, Sedlaczek O, Hahn HK (2015) A software tool for aligning and linking morphological CT, quantitative DCE- and DWI-MRI with morphological CT and 3D pathology in lung cancer staging and tumor biology. Radiological Society of North America. QRR008
Laue H, Kohlmann P, Lotz J, Sedlaczek O, Müller B, Breuhahn K, Grabe N, Warth A, Hahn HK (2015) Software Support for Combined Staging of Lung Cancer in CT, Functional MRI and Pathology. Proc. of the 16th World Conference on Lung Cancer
Liu Y, Wang J, Daams M, Weiler F, Hahn HK, Duan Y, Huang J, Ren Z, Ye J, Dong H, Vrenken H, Wattjes M, Barkhof F, Shi FD, Li K (2015) Differential Atrophy Patterns of Spinal Cord and Brain in Neuromyelitis Optica and Multiple Sclerosis. Neurology 84(14):1465–72
Lukas C, Knol DL, Sombekke MH, Bellenberg B, Hahn HK, Popescu V, Weier K, Radue EW, Gass A, Kappos L, Naegelin Y, Uitdehaag BMJ, Geurts JJG, Barkhof F, Vrenken H (2015) Cervical spinal cord volume loss is related to clinical disability progression in multiple sclerosis. J Neurol Neurosurg Psychiatry 86(4):410–418
Nitsch J, Klein J, Dammann P, Miller D, Wrede K, Sure U, Hahn HK (2015) Automatic segmentation of perifalcine structures in two-dimensional ultrasound images using object-based image analysis. Proc. of CURAC 2015. pp 219–224
Nitsch J, Klein J, Miller D, Sure U, Hahn HK (2015) Automatic Segmentation of the Cerebral Falx and Adjacent Gyri in 2D Ultrasound Images. Bildverarbeitung für die Medizin 2015. pp 287–292
Paetz T, Harz M, Wang L, Stoecker C, Schilling K, Colletta J, Schlooz-Vries M, Hahn HK, Georgii J (2015) Sliding Motion in Breast Deformation Modeling. Proc. of 3rd MICCAI Workshop on Breast Image Analysis. pp 137–144
Paetz T, Waltermann C, Angelmahr M, Ojdanic D, Schade W, Witte M, Hahn HK (2015) Integration of fiber optical shape sensing with medical visualization for minimal-invasive interventions. Proc. of SPIE Medical Imaging: Image-Guided Procedures, Robotic Interventions, and Modeling. 94150Z:pp 1–6
Razavi M, Wang L, Gubern-Mérida A, Ivanovska T, Laue H, Karssemeijer N, Hahn HK (2015) Towards Accurate Segmentation of Fibroglandular Tissue in Breast MRI Using Fuzzy C-Means and Skin-Folds Removal. Proc. Image Analysis and Processing — ICIAP 2015. pp 528–536
Stoecker C, Harz M, Schlooz-Vries M, Mann R, Schilling K, Colletta J, Georgii J, Paetz T, Hahn HK (2015) MRI-based visualization and augmented reality for breast surgery planning and guidance. Proc. of CURAC 2015. pp 285–286
Wang L, Strehlow J, Ruehaak J, Weiler F, Diez Y, Gubern-Mérida A, Diekmann S, Laue H, Hahn HK (2015) A fast alignment method for breast MRI follow-up studies using automated breast segmentation and current-prior registration. Proc. of SPIE Medical Imaging: Image Processing. 941334:pp 1–8
Weiler F, Hahn HK (2015) Fast and intuitive segmentation of gyri of the human brain. Proc. of SPIE Medical Imaging: Image-Guided Procedures, Robotic Interventions, and Modeling. 941517:pp 1–6
Weiler F, Chlebus G, Rieder C, Moltz J, Waring A, Brachmann C, Traulsen N, Corr D, Wirtz S, Krass S, Hahn HK (2015) Building Blocks for Clinical Research in Adaptive Radiotherapy. Proc. of CURAC 2015. pp 139–144
Weiler F, Daams M, Lukas C, Barkhof F, Hahn HK (2015) Highly accurate volumetry of the spinal cord. Proc. of SPIE Medical Imaging: Image Processing. 941302:pp 1–6
Weiler F, Brachmann C, Traulsen N, Nijhuis R, Chlebus G, Schenk M, Corr D, Wirtz S, Ganswindt U, Thieke C, Belka C, Hahn HK (2015) Fast automated non-linear contour propagation for adaptive head and neck radiotherapy. MICCAI Workshop on Imaging and Computer Assistance in Radiation Therapy ICART

2014

Acevedo C, Chitiboi T, Linsen L, Hahn HK (2014) Automatic Classification of Salient Boundaries in Object-Based Image Segmentation. Bildverarbeitung für die Medizin. Springer, pp 396–399
Al-Taie A, Hahn HK, Linsen L (2014) Uncertainty estimation and visualization in probabilistic segmentation. Comput Graph 39:48–59
Al-Taie A, Hahn HK, Linsen L (2014) Uncertainty-aware Ensemble of Classifiers for Segmenting Brain MRI Data. Eurographics Workshop on Visual Computing for Biology and Medicine, VCBM 2014, Vienna, Austria, 2014. Proceedings. pp 41–50
Chitiboi T, Hennemuth A, Linsen L, Hahn HK (2014) Automatic Detection of Heart Function and Breathing Phase in Real-time Cardiac MRI. Proc. Computer Assisted Radiology and Surgery – Segmentation. pp S41–S42
Chitiboi T, Hennemuth A, Tautz L, Huellebrand M, Frahm J, Hahn HK (2014) Cardiac Function Analysis in Multi-cycle Real-time MRI. Proceedings of the Joint Annual Meeting ISMRM-ESMRMB. 3929
Chitiboi T, Hennemuth A, Tautz L, Hüllebrand M, Frahm J, Linsen L, Hahn HK (2014) Context-Based Segmentation and Analysis of Multi-Cycle Real-Time Cardiac MRI. Proceedings of IEEE International Symposium on Biomedical Imaging. pp 943–946
Daams M, Weiler F, Steenwijk MD, Hahn HK, Geurts JJ, Vrenken H, van Schijndel RA, Balk LJ, Tewarie PK, Tillema J-M, Killestein J, Uitdehaag BM, Barkhof F (2014) Mean upper cervical cord area (MUCCA) measurement in long-standing multiple sclerosis: Relation to brain findings and clinical disability. Mult Scler 20(14):1860–1865
Georgii J, Bartscherer T, Degel C, Fonfara H, Hewener H, Kipshagen T, Kocev B, Lotz J, Ojdanic D, Olesch J, Rothlübbers S, Speicher D, Tretbar S, Hahn HK, Günther M (2014) Improving Breast Biopsies by Motion Tracking. Proc. of Image-Guided Interventions (IGIC). pp 79–80
Hansen C, Heckel F, Ojdanic D, Schenk A, Zidowitz S, Hahn HK (2014) Genauigkeit und Fehlerquellen im Operationssaal am Beispiel der Leberchirurgie. In: Niederlag W et al. (ed) Der digitale Operationssaal. Health Academy, pp 69–87
Hansen C, Zidowitz S, Preim B, Stavrou G, Oldhafer KJ, Hahn HK (2014) Impact of model-based risk analysis for liver surgery planning. Int J CARS 9(3):473–480
Heckel F, Meine H, Moltz JH, Kuhnigk J-M, Heverhagen JT, Kießling A, Buerke B, Hahn HK (2014) Segmentation-Based Partial Volume Correction for Volume Estimation of Solid Lesions in CT. IEEE Trans Med Imaging 33(2):462–480
Heckel F, Moltz JH, Meine H, Geisler B, Kießling A, D'Anastasi M, Pinto dos Santos D, Theruvath AJ, Hahn HK (2014) On the Evaluation of Segmentation Editing Tools. SPIE J Med Imag 1(3):034005
Klein J, Weiler F, Hahn HK (2014) Probabilistic Parameter Adaption for Fiber Tracking of the Corticospinal Tract. Proc. of MICCAI DTI Tractography Challenge
Kocev B, Georgii J, Linsen L, Hahn HK (2014) Information Fusion for Real-time Motion Estimation in Image-guided Breast Biopsy Navigation. In: Bender J, Duriez C, Jaillet F, Zachmann G (eds) Proc. of Workshop on Virtual Reality Interaction and Physical Simulation (VRIPHYS). Eurographics Association, pp 87–98
Laue HOA, Kohlmann P, Dicken V, Moltz J, Sedlaczek O, Olesch J, Lotz J, Kikinis R, Hahn HK (2014) An application for comparing quantitative DCE- and DWI-MRI with pathology supporting investigators correlating radiology, pathology and tumor biology in lung cancer. Annual Meeting Radiological Society of North America (RSNA). QRR005
Rieder C, Geisler B, Bruners P, Isfort P, Na H-S, Mahnken AH, Hahn HK (2014) Software-Assisted Post-Interventional Assessment of Radiofrequency Ablation. Proceedings of SPIE Medical Imaging. 903604:1–8
Ristovski G, Preusser T, Hahn HK, Linsen L (2014) Uncertainty in medical visualization: Towards a taxonomy. Comput Graph 39:60–73
Schenk A, Chen L, Yoon JH, Lee JM, Bergmann K, Laue HOA, Strehlow J, Schumann C, Demedts D, Hahn HK (2014) Combined analysis of dynamic Gd-EOB-DTPA-enhanced MRI and local volume computation for quantitative liver function evaluation. Annual Meeting Radiological Society of North America (RSNA). QRR004
Schwier M, Hahn HK (2014) Segmentation Hierarchies and Border Features for Automatic Pregnancy Detection in Porcine Ultrasound. IEEE International Symposium on Biomedical Imaging. pp 931–934
Wang L, Böhler T, Zöhrer F, Georgii J, Rauh C, Fasching PA, Brehm B, Schulz-Wendtland R, Beckmann MW, Uder M, Hahn HK (2014) Fully Automated Nipple Detection in 3D Breast Ultrasound Images. 12th International Workshop on Breast Imaging. pp 64–71
Wang L, Hansen C, Zidowitz S, Hahn HK (2014) Segmentation and Separation of Venous Vasculatures in Liver CT Images. SPIE Medical Imaging: Computer-Aided Diagnosis. 90350Q:pp 1–8
Wang L, Harz M, Boehler T, Platel B, Homeyer A, Hahn HK (2014) A robust and extendable framework towards fully automated diagnosis of nonmass lesions in breast DCE-MRI. IEEE International Symposium on Biomedical Imaging. pp 129–132
Wang L, Böhler T, Zöhrer F, Georgii J, Rauh C, Fasching PA, Brehm B, Schulz-Wendtland R, Beckmann MW, Uder M, Hahn HK (2014) A hybrid method towards automated nipple detection in 3D breast ultrasound images. IEEE Engineering in Medicine and Biology Society (EMBC’14). pp 2869–2872

2013

Bauer MHA, Kuhnt D, Barbieri S, Klein J, Becker A, Freisleben B, Hahn HK, Nimsky C (2013) Reconstruction of White Matter Tracts via Repeated Deterministic Streamline Tracking – Initial Experience. PLoS ONE 8(5):e63082
Black D, Al Issawi J, Rieder C, Hahn HK (2013) Enhancing Medical Needle Placement with Auditory Display. Mensch & Computer 2013: Interaktive Vielfalt. Oldenbourg Verlag, pp 289–292
Black D, Al Issawi J, Hansen C, Rieder C, Hahn HK (2013) Auditory Support for Navigated Radiofrequency Ablation. Proceedings of CURAC. Innsbruck, Austria, pp 30–33
Chitiboi T, Hennemuth A, Tautz L, Stolzmann P, Donati OF, Linsen L, Hahn HK (2013) Automatic Detection of Myocardial Perfusion Defects using Object-based Myocardium Segmentation. Computing in Cardiology. IEEE, pp 639–642
Chitiboi T, Homeyer A, Linsen L, Hahn HK (2013) Object-Based Boundary Properties. Bildverarbeitung für die Medizin. Springer, pp 199–204
Chitiboi T, Hennemuth A, Linsen L, Hahn HK (2013) Towards Automatic Extraction of the Myocardium in Temporal MRI Using Object-based Segmentation. Visualization in Medicine and Life Sciences (VMLS). Springer Berlin-Heidelberg, pp 13–17
Drexl J, Khan H, Markl M, Hennemuth A, Meier S, Lorenz R, Hahn HK (2013) Detection of Vortical Structures in 4D Velocity Encoded Phase Contrast MRI Data Using Vector Template Matching. 7th International Conference on Functional Imaging and Modeling of the Heart. pp 276–283
Drexl J, Mirzaee H, Harloff A, Hüllebrand M, Hennemuth A, Hahn HK (2013) A Software Tool for the Computation of Arterial Pulse Wave Velocities from Flow-sensitive 4D MRI Data. Computing in Cardiology. pp 559–562
Fasching PA, Rauh C, Jud SM, Radicke M, Linde I, Wittenberg T, Wagner F, Zöhrer F, Georgii J, Hahn HK, Brehm B, Uder M, Beckmann MW, Schulz-Wendtland R (2013) Dreidimensionale Beurteilung der Brustzusammensetzung mit dem Automatisierten Brust-Volumen-Scanner (ABVS). 33. Jahrestagung Deutsche Gesellschaft für Senologie
Georgii J, Zöhrer F, Hahn HK (2013) Model-based Position Correlation between Breast Images. Proceedings of SPIE Medical Imaging. 86701U:pp 1–7
Gubern-Mérida A, Wang L, Kallenberg M, Martí R, Hahn HK, Karssemeijer N (2013) Breast segmentation in MRI: quantitative evaluation of three methods. Proceedings of SPIE Medical Imaging. 86693G:pp 1–7
Hansen C, Black D, Lange C, Rieber F, Lamade W, Donati M, Oldhafer KJ, Hahn HK (2013) Auditory support for resection guidance in navigated liver surgery. Int J Med Robot 9(1):36–43
Hansen C, Zidowitz S, Ritter F, Lange C, Oldhafer KJ, Hahn HK (2013) Risk maps for liver surgery. Int J CARS 8(3):419–428
Heckel F, Ivanov MI, Moltz JH, Hahn HK (2013) Toward Automated Validation of Sketch-based 3D Segmentation Editing Tools. Proceedings of Scandinavian Conferences on Image Analysis. Lecture Notes in Computer Science, pp 256–265
Heckel F, Moltz JH, Tietjen C, Hahn HK (2013) Sketch-Based Editing Tools for Tumour Segmentation in 3D Medical Images. Comput Graph Forum 32(8):144–157
Homeyer A, Schenk A, Arlt J, Dahmen U, Dirsch O, Hahn HK (2013) Practical quantification of necrosis in histological whole-slide images. Comput Med Imaging Graph 37(4):313–322
Klein J, Meuschke M, Geisler B, Hahn HK (2013) Local Atlas-based Adaptive Fiber Tracking. Proc. of MICCAI 2013 – DTI Tractography Challenge
Laue HOA, Oei MTH, Chen L, Kompan IN, Hahn HK, Prokop M, Mannesing R (2013) Automated artery and vein detection in dynamic CT data with an unsupervised classification algorithm of the time intensity curves. Proceedings of SPIE Medical Imaging. 86691W:pp 1–6
Moltz JH, Steinberg C, Geisler B, Hahn HK (2013) A tool for efficient creation of probabilistic expert segmentations. Medical Image Understanding and Analysis. pp 7–12
Pener I, Schmidt M, Hahn HK (2013) Towards Fully Automated Tracking of Carotid and Vertebral Arteries in CT Angiography. Bildverarbeitung für die Medizin. pp 181–186
Rieder C, Brachmann C, Hofmann B, Klein J, Köhn A, Ojdanic D, Schumann C, Weiler F, Hahn HK (2013) Interactive Visualization of Neuroanatomical Data for a Hands-On Multimedia Exhibit. EuroVis Workshop on Visualization in Medicine and Life Sciences (VMLS). pp 37–41
Schwier M, Chitiboi T, Hülnhagen T, Hahn HK (2013) Automated spine and vertebrae detection in CT images using object-based image analysis. Int J Numer Method Biomed Eng 29(9):938–963
Schwier M, Hahn HK, Dirsch O, Böhler T, Dahmen U (2013) Registration of histological whole slide images guided by vessel structures. J Pathol Inform 4(2):S10
Schwier M, Hahn HK, Dahmen U, Dirsch O (2013) Reconstruction of Vessel Structures from Serial Whole Slide Sections of Murine Liver Samples. Proceedings of SPIE Medical Imaging. 86760D:pp 1–10
Srikantha A, Harz M, Newstead G, Wang L, Platel B, Mann RM, Hahn HK, Peitgen HO (2013) Symmetry-Based Detection and Diagnosis of DCIS in Breast MRI. Proceedings of SPIE Medical Imaging. 86701E:pp 1–8
van Straaten D, Brachmann C, Weidner A, Kohlmann P, Dinter D, Schoenberg S, Hahn HK (2013) Software prototype to support follow-up analysis of multi-parametric MR images. International Journal of Computer Assisted Radiology and Surgery. pp 45–46
Wang L, Hansen C, Zidowitz S, Hahn HK (2013) Interactive Segmentation of Vascular Structures in CT Images for Liver Surgery Planning. Deutsche Gesellschaft für Computer- und Roboterassistierte Chirurgie. pp 98–102

2012

Barbieri S, Klein J, Bauer MHA, Nimsky C, Hahn HK (2012) Atlas-based fiber reconstruction from diffusion tensor MRI data. Int J CARS 7(6):959–967
Barbieri S, Bauer MHA, Klein J, Moltz J, Nimsky C, Hahn HK (2012) DTI Segmentation via the Combined Analysis of Connectivity Maps and Tensor Distances. Neuroimage 60(2):1025–1035
Boehler T, Zoehrer F, Harz M, Hahn HK (2012) Breast Image Registration and Deformation Modeling. Crit Rev Biomed Eng 40(3):235–258
Drexl JB, Hennemuth A, Meier S, Lorenz R, Bock J, Harloff A, Markl M, Hahn HK (2012) A tool for the interactive analysis and exploration of in-vivo haemodynamics from 4D PC MRI. J Cardiovasc Mag Reson 14(1):W70
Heckel F, Braunewell S, Soza G, Tietjen C, Hahn HK (2012) Sketch-based Image-independent Editing of 3D Tumor Segmentations using Variational Interpolation. Eurographics Workshop on Visual Computing for Biomedicine. pp 73–80
Klein J, Köhler B, Hahn HK (2012) Efficient global fiber tracking on multidimensional diffusion direction maps. Proceedings SPIE Medical Imaging 2012: Image Processing. 83140M:pp 1–8
Klein J, Weiler F, Barbieri S, Hirsch JG, Geisler G, Hahn HK (2012) Quantitative neuroimaging advances. ECR Today 2012, Saturday 3 March 23
Pietrzyk MW, Zöhrer F, Harz MT, McEntee M, Hahn HK, Haygood T, Evanoff MG, Brennan PC (2012) Effect of morphing between unenhanced and multiscale enhanced chest radiographs on pulmonary nodule detection. Proceedings of SPIE Medical Imaging: Image Perception, Observer Performance, and Technology Assessment. 831816:pp 1–8
Schwier M, Boehler T, Hahn HK, Dahmen U, Dirsch O (2012) Registration of histological whole slide images guided by vessel structures. MICCAI Workshop on Histopathology Image Analysis: Image Computing in Digital Pathology. pp 147–158
Srikantha A, Harz M, Wang L, Platel B, Mann RM, Hahn HK, Peitgen H-O (2012) Symmetry-based detection of ductal carcinoma in situ in breast MRI. Proc. International Congress on MR-Mammography. pp 158–159
Wang L, Moltz JH, Bornemann L, Hahn HK (2012) A Minimally-interactive Method to Segment Enlarged Lymph Nodes in 3D Thoracic CT Images Using a Rotatable Spiral-Scanning Technique. Proc. SPIE Medical Imaging. 83150D:pp 1–8
Wang L, Platel B, Ivanovskaya T, Harz M, Hahn HK (2012) Fully automatic breast segmentation in 3D breast MRI. IEEE International Symposium on Biomedical Imaging. pp 1024–1027
Weiler F, Rieder C, David CA, Wald C, Hahn HK (2012) On the Value of Multi-Volume Visualization for Preoperative Planning of Cerebral AVM Surgery. Eurographics Workshop on Visual Computing for Biomedicine. pp 49–56

2011

Barbieri S, Bauer MHA, Klein J, Nimsky C, Hahn HK (2011) Segmentation of fiber tracts based on an accuracy analysis on diffusion tensor software phantoms. Neuroimage 55(2):532–544
Bauer MHA, Barbieri S, Klein J, Egger J, Kuhnt D, Freisleben B, Hahn HK, Nimsky C (2011) Boundary estimation of fiber bundles derived from diffusion tensor images. Int J CARS 6(1):1–11
Eichler L, Bellenberg B, Hahn HK, Koster O, Schols L, Lukas C (2011) Quantitative Assessment of Brain Stem and Cerebellar Atrophy in Spinocerebellar Ataxia Types 3 and 6: Impact on Clinical Status. Am J Neuroradiol 32(5):890–897
Harz M, Georgii J, Schilling K, Hahn HK (2011) Real-time breast deformation using non-linear tissue properties. Informatik 2011: Workshop Emerging Technologies for Medical Diagnosis and Therapy
Harz M, Georgii J, Schilling K, Hahn HK (2011) Towards Navigated Breast Surgery Using Efficient Breast Deformation Simulation. Proc. of Workshop on Breast Image Analysis. pp 137–144
Heckel F, Konrad O, Hahn HK, Peitgen H-O (2011) Interactive 3D Medical Image Segmentation with Energy-Minimizing Implicit Functions. Comput Graph 35(2):275–287
Homeyer A, Dahmen U, Huang H, Schenk A, Dirsch O, Hahn HK (2011) A comparison of sampling strategies for histological image analysis. J Pathol Inform 2(2):11
Ivanovska T, Linsen L, Hahn HK, Völzke H (2011) GPU implementations of a relaxation scheme for image partitioning: GLSL versus CUDA. Comput Vis Sci 14(5):217–226
Kiy G, Lehmann P, Hahn HK, Eling P, Kastrup A, Hildebrandt H (2011) Decreased hippocampal volume, indirectly measured, is associated with depressive symptoms and consolidation deficits in multiple sclerosis. Mult Scler 17(9):1088–1097
Klein J, Barbieri S, Bauer MHA, Nimsky C, Hahn HK (2011) Benchmarking the Quality of Diffusion-Weighted Images
Klein J, Weiler F, Barbieri S, Hirsch JG, Geisler B, Hahn HK (2011) NeuroQLab – An Extendible Software Assistant for Efficient and Reproducible Evaluation of Neuroimaging Data. Proceedings of European Congress on Radiology (ECR 2011)
Lukas C, Bellenberg B, Koster O, Greschner S, Hahn HK (2011) A new sulcus-corrected approach for assessing cerebellar volume in spinocerebellar ataxia. Psychiatry Res 193(2):123–130
Mang S, Brachmann C, Köhn A, van Straaten D, Floca R, Merkel B, Nagel A, Biller A, Tautz L, Oesau S, Genz A, Wirtz S, Unholtz D, Gerigk L, Parodi K, Süss P, Hahn HK, Thieke C, Woetzel J (2011) RONDO – Software platform used for combined analysis and image display for MR and other diagnostic modalities. ESMRMB 2011, 28th Annual Scientific Meeting, Leipzig, Germany, 6-8 October. 534–535
Merkel B, Harz MT, Hahn HK (2011) MISSA – A highly-developed clinical tool for MR-Spectroscopy. International Society for Magnetic Resonance in Medicine. 3479
Moltz JH, Rühaak J, Hahn HK, Peitgen H-O (2011) A Novel Adaptive Scoring System for Segmentation Validation with Multiple Reference Masks. Proc SPIE Medical Imaging. 796214:pp 1–10
Moltz JH, Braunewell S, Rühaak J, Heckel F, Barbieri S, Tautz L, Hahn HK, Peitgen H-O (2011) Analysis of Variability in Manual Liver Tumor Delineation in CT Scans. IEEE International Symposium on Biomedical Imaging. pp 1974–1977
Renz DM, Hahn HK, Schmidt P, Rexilius J, Lentschig M, Pfeil A, Sauner D, Fitzek C, Mentzel HJ, Kaiser WA, Reichenbach JR, Bottcher J (2011) Accuracy and reproducibility of a novel semi-automatic segmentation technique for MR volumetry of the pituitary gland. Neuroradiology 53(4):233–244
Rieder C, Kröger T, Schumann C, Hahn HK (2011) GPU-Based Real-Time Approximation of the Ablation Zone for Radiofrequency Ablation. IEEE Trans Vis Comput Graph 17(12):1812–1821
Rieder C, Palmer S, Link F, Hahn HK (2011) A Shader Framework for Rapid Prototyping of GPU-Based Volume Rendering. Comput Graph Forum 3(30):1031–1040
Schwier M, Chitiboi T, Bornemann L, Hahn HK (2011) An Object-based Image Analysis Approach to Spine Detection in CT Images. Proceedings of the III ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing: VipIMAGE. pp 173–178
Székely G, Hahn HK (2011) Proceedings of the 22nd International Conference on Information Processing in Medical Imaging, IPMI 2011. Springer, Berlin Heidelberg, LNCS (6801)
van Straaten D, Hintze C, Strehlow J, Boehler T, Krass S, Hahn HK (2011) Automatic Lung Lobe Segmentation in DCE-MRI Images by Image Registration of Lung CT and MR Images and Transfer of CT-based Lobe Segmentations. ESMRMB 2011, 28th Annual Scientific Meeting, Leipzig, Germany, 6-8 October. 400–401
Wang L, Kohnen M, Friman O, Hahn HK (2011) Fast automated segmentation of femoral heads in fluoroscopic X-ray images. IEEE International Symposium on Biomedical Imaging. IEEE, pp 984–988
Wang L, Zoehrer F, Friman O, Hahn HK (2011) A fully automatic method for nipple detection in 3D breast ultrasound images. Proc. Computer Assisted Radiology and Surgery. 191
Wang L, Filippatos K, Friman O, Hahn HK (2011) Fully automated segmentation of the pectoralis muscle boundary in breast MR images. Proc. SPIE Medical Imaging: Computer-Aided Diagnosis. 796309:pp 1–8
Wang L, Kohnen M, Friman O, Hahn HK (2011) Fast Automated Segmentation of Femoral Heads in Fluoroscopic X-Ray Images. Proceedings of the 8th International Symposium on Biomedical Imaging. pp 984–988
Weiler F, Hahn HK (2011) An interactive ROI tool for DTI fiber tracking. Proceedings of SPIE Medical Imaging: Visualization, Image-Guided Procedures, and Modeling. 796437
Zidowitz S, Hahn HK, Peitgen H-O (2011) Risikovermeidung durch modellbasierte Computerunterstützung von Diagnose und Therapie. Endo heute 24(4):252–256

2010

Barbieri S, Bauer MHA, Klein J, Nimsky C, Hahn HK (2010) A Variational, Non-Parametric Approach to the Fuzzy Segmentation of Diffusion Tensor Images. Proceeding of MICCAI workshop on Computational Diffusion MRI. pp 134–145
Barbieri S, Klein J, Nimsky C, Hahn HK (2010) Assessing fiber tracking accuracy via diffusion tensor software models. Proceedings of SPIE Medical Imaging. 762326:pp 1–9
Barbieri S, Klein J, Nimsky C, Hahn HK (2010) Towards Image-Dependent Safety Hulls for Fiber Tracking. Proceedings of the Joint Annual Meeting ISMRM-ESMRMB. 1672
Bauer M, Barbieri S, Klein J, Egger J, Kuhnt D, Hahn HK, Freisleben B, Nimsky C (2010) A Ray-based Approach for Boundary Estimation of Fiber Bundles derived from Diffusion Tensor Imaging. Proceedings of Computer Assisted Radiology and Surgery. pp 47–48
Bauer M, Egger J, O'Donnell T, Barbieri S, Klein J, Hahn HK, Freisleben B, Nimsky C (2010) A Fast and Robust Graph-based Approach for Boundary Estimation of Fiber Bundles Based on Fractional Anisotropy Maps. Proceedings of 20th International Conference on Pattern Recognition. pp 4016–4019
Bauer MHA, Egger J, Barbieri S, Klein J, Kuhnt D, Hahn HK, Freisleben B, Nimsky C (2010) Ray-Based and Graph-Based Methods for Fiber Bundle Boundary Estimation. Proceedings of the Biosignal 2010: International Biosignal Processing Conference
Bauer MHA, Egger J, Kuhnt D, Barbieri S, Klein J, Hahn HK, Freisleben B, Nimsky C (2010) A Semi-Automatic Graph-Based Approach for Determining the Boundary of Eloquent Fiber Bundles in the Human Brain. Proc. DGBMT. Rostock
Boehler T, Schilling K, Bick U, Hahn HK (2010) Deformable Image Registration of Follow-up Breast MR Images. Proceedings of WBIR. LNCS 2604, pp 13–24
Fink F, Klein J, Lanz M, Mitrovics T, Lentschig M, Hahn HK, Hildebrandt H (2010) Comparison of diffusion tensor-based tractography and quantified brain atrophy for analyzing demyelination and axonal loss in MS. J Neuroimaging 20(4):334–344
Georg M, Preusser T, Hahn HK (2010) Global Constructive Optimization of Vascular Systems. Department of Computer Science & Engineering - Washington University, St. Louis, 1–13
Hahn HK, Harz M, Seyffarth H, Zoehrer F, Boehler T, Filippatos K, Wang L, Homeyer A, Ritter F, Laue H, Guenther M, Twellmann T, Tabár L, Bick U, Schilling K (2010) Concepts for Efficient and Reliable Multi-Modal Breast Image Reading. 10th International Workshop on Digital Mammography (IWDM 2010). Springer, Girona, pp 121–128
Homeyer A, Schwier M, Hahn HK (2010) A Generic Concept for Object-Based Image Analysis. Proceedings of the International Conference on Computer Vision Theory and Applications. pp 530–533
Ivanovska T, Schenk A, Homeyer A, Deng M, Dahmen U, Dirsch O, Hahn HK, Linsen L (2010) A fast and robust hepatocyte quantification algorithm including vein processing. BMC Bioinformatics 11:124
Karssemeijer N, Huisman H, Hawkes D, Hipwell J, Boehler T, Lesniak J, Tanner C, Szekely G, Niessen W, Hahn HK (2010) Integrating Biological Knowledge, Novel Imaging Modalities, and Modeling in Breast Cancer Diagnosis. Proc. 1st Virtual Physiological Human Conference. Brussels, pp 424–426
Klein J, Barbieri S, Stuke H, Bauer M, Egger J, Nimsky C, Hahn HK (2010) On the Reliability of Diffusion Neuroimaging. In: Cristina Marta Del-Ben (ed) NeuroImaging. InTech, pp 1–24
Klein J, Erhard P, Hahn HK (2010) Resolution-Dependent Differences in Fiber Tracking and Quantification of the Visual Pathways. Proceedings of the Joint Annual Meeting ISMRM-ESMRMB. 1660
Klein J, Grötsch A, Betz D, Barbieri S, Friman O, Stieltjes B, Hildebrandt H, Hahn HK (2010) Qualitative and quantitative analysis of probabilistic and deterministic fiber tracking. Proceedings of SPIE Medical Imaging. 76232A:pp 1–8
Klein J, Scholl M, Köhn A, Hahn HK (2010) Real-time fiber selection using the Wii remote. Proceedings of SPIE Medical Imaging. 76250N:pp 1–8
Laue H, Dolschel D, Gremse F, Hahn HK, Klingmueller U, Drasdo D, Kiessling F (2010) Averaged functions for contrast agent concentration with heart rate measurements from Dynamic Contrast Enhanced Magnetic Resonance Imaging in Mice. System Biology of Mammalian Cells. pp 162–163
Laue H, Hennemuth A, Diehl V, Harz MT, Hahn HK, Peitgen H-O (2010) Influence of contrast arrival time and temporal resolution in diagnosis of breast cancer with DCE-MRI. Proceedings of the 18th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM). Stockholm, Sweden, 5190
Merkel B, Nehen F, Oezdemir Y, Harz MT, Leibfritz D, Fahlbusch R, Hahn HK (2010) Classification on ex-vivo MRS signals of glioma samples. Proceedings of the 18th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM). 4000
Zachow S, Hahn HK, Lange T (2010) Computerassistierte Chirurgieplanung. In: Schlag PM Eulenstein S Lange T (ed) Computerassistierte Chirurgie. Urban&Fischer, Elsevier, München, pp 119–150
Zöhrer F, Harz MT, Bödicker A, Seyffarth H, Schilling KJ, Tabár LK, Hahn HK (2010) Interactive Multi-scale Contrast Enhancement of Previously Processed Digital Mammograms. Proceeding International Workshop on Digital Mammography. Girona, pp 31–38
Zoehrer F, Drexl J, Hahn HK (2010) Speckle Reduction for Automated Breast Ultrasound: A Comparison of Three Filtering Methods. Bildverarbeitung für die Medizin. pp 390–394

2009

Bellenberg B, Schimrigk S, Brück K, Tönnes C, Chan A, Klein J, Hahn HK, Köster O, Lukas C (2009) Third ventricle enlargement correlates to different patterns of regional fiber integrity in the corpus callosum of relapsing-remitting and secondary progressive multiple sclerosis patients. Multiple Sclerosis ECTRIMS. Düsseldorf, pp 91–92
Giesel FL, Hart AR, Hahn HK, Wignall E, Rengier F, Talanow R, Wilkinson ID, Zechmann CM, Weber M-A, Kauczor HU, Essig M, Griffiths PD (2009) 3D reconstructions of the cerebral ventricles and volume quantification in children with brain malformations. Acad Radiol 16(5):610–617
Giesel FL, Zechmann C, Talanow R, Gerigk L, Zamecnik P, Hahn HK, Essig M, Laue H (2009) Automated combined voxel based kinetic analysis of DCE- and DSC-MRI in brain lesions. Proceedings of the 22nd International Congress and Exhibition of Computer Assisted Radiology and Surgery (CARS). S14
Hansen C, Zidowitz S, Hindennach M, Schenk A, Hahn HK, Peitgen HO (2009) Interactive determination of robust safety margins for oncologic liver surgery. Int J CARS 4(5):469–474
Harz MT, Schilling K, Hahn HK (2009) Software Tools for Breast Cancer Detection in Positron Emission Mammography Images. Lecture Notes in Informatics. Informatik 2009 – Im Focus das Leben, pp 1370–1377
Hennemuth A, Harloff A, Spehl T, Pavlov N, Friman O, Paul D, von Elverfeldt D, Kuehnel C, Hahn HK, Hennig J, Markl M (2009) Visual classification of complicated plaques based on multidimensional image fusion. GI Workshop Softwareassistenten. Gesellschaft fuer Informatik (GI), pp 1359–1369
Klein J, Laun F, Erhard P, Diehl V, Hahn HK (2009) On the Reliability of Quantitative Volumetric and Structural Neuroimaging. J Imaging Decisions MRI 12(3):2–10
Laue H, Behrens S, Zechmann CM, Zamecnik P, Hahn HK, Peitgen H-O (2009) Statistical Comparison of Tofts-model Parameters with Descriptive and Approximated Descriptive Parameters. Proceedings of the 17th ISMRM Scientific Meeting & Exhibition. 2271
Loose J, Harz M, Laue H, Twellmann T, Bick U, Rominger M, Hahn HK, Peitgen HO (2009) Assessment of texture analysis on DCE-MRI data for the differentiation of breast tumor lesions. Proc SPIE Medical Imaging. 72600K:pp 1–12
Lukas C, Bellenberg B, Hahn HK, Rexilius J, Drescher R, Hellwig K, Koster O, Schimrigk S (2009) Benefit of repetitive intrathecal triamcinolone acetonide therapy in predominantly spinal multiple sclerosis: prediction by upper spinal cord atrophy. Ther Adv Neurol Disord 2(6):42–49
Merkel B, Harz MT, Massé K, Hahn HK (2009) Advanced Software Assistance in MR Spectroscopy. Book Of Abstracts, ESMRMB 2009. pp 316–317
Nix O, Koehn A, Siems U, Hahn HK, Thieke C (2009) DIROlab – A software tool for visualization and evaluation of data from diagnostic imaging and radiotherapy. In: Dössel O, Schlegel WC (eds) World Congress on Medical Physics and Biomedical Engineering. Springer-Verlag, München, pp 1333–1336
Seyffarth H, Geisler B, Peitgen H-O, Hahn HK (2009) Who may benefit from a combined review of radiologic and pathologic images of breast diseases? In: Dössel O, Schlegel WC (eds) World Congress on Medical Physics and Biomedical Engineering. Springer-Verlag, München, pp 866–867
Thieke C, Nix O, Köhn A, Floca R, van Straaten D, Hahn HK, Strauss LG, Siems U, Graf M, Prüm H, Klein J, Laue H, Kaster F, Hamprecht FA, Simon D, Stieltjes B, Debus J, Huber PE (2009) Ein Framework und Multi-Applikations-Prototyp für integrierte radiologische Diagnostik und Strahlentherapie. DEGRO 2009 15. Jahreskongress der Deutschen Gesellschaft für Radioonkologie, Radioonkologie · Medizinische Physik · Strahlenbiologie. p 81
van Straaten D, Zamecnik P, Boehler T, Laue H, Wirtz S, Hahn HK (2009) Automatic Registration of DCE-MRI Prostate Images for Follow-up Comparison. World Congress on Medical Physics and Biomedical Engineering. IFMBE Proceedings, pp 1452–1455
Weiler F, Rexilius J, Klein J, Hahn HK (2009) NeuroQLab – A Software Assistent for Neurosurgical Planning and Quantitative Image Analysis. Lecture Notes in Informatics. Lübeck, pp 1485–1491
Zidowitz S, Schenk A, Hindennach M, Hansen C, Hahn HK, Peitgen H-O (2009) Reliability and Robustness in Image Based Surgical Planning. In: Dössel O, Schlegel WC (eds) World Congress on Medical Physics and Biomedical Engineering. IFMBE Proceedings 25(4), pp 1628–1631

2008

Asbach P, Canda V, Hermann K-GA, Krug L, Hahn HK, Hamm B, Klessen C (2008) Efficient whole-body MRI interpretation: evaluation of a dedicated software prototype. J Digit Imaging 21(1):50–58
Bellenberg B, Lukas C, Haghikia A, Fischer M, Klein J, Hahn HK, Beste C, Hausmann M, Köster O, Schimrigk SK (2008) Regional fiber degeneration in the corpus callosum monitored by fractional anisotropy correlates to FLAIR hypodensities and black holes in MS patients. European Radiology. Proceesings of the European Congress of Radiology (ECR), 2008
Fritzsche KH, Giesel FL, Heimann T, Thomann PA, Hahn HK, Pantel J, Schröder J, Essig M, Meinzer HP (2008) Neurodegenerative changes in Alzheimer's disease: a comparative study of manual, semi-automated, and fully automated assessment using MRI. Proc. SPIE Medical Imaging: Computer-Aided Diagnosis. 69151V:pp 1–10
Fritzsche KH, Giesel FL, Thomann PA, Hahn HK, Essig M, Meinzer H-P (2008) Quantifizierung neurodegenerativer Veränderungen bei der Alzheimer Krankheit – Evaluierung eines automatischen Verfahrens. Bildverarbeitung für die Medizin. pp 363–367
Giesel FL, Thomann PA, Hahn HK, Politi M, Stieltjes B, Weber MA, Pantel J, Wilkinson ID, Griffiths PD, Schroder J, Essig M (2008) Comparison of manual direct and automated indirect measurement of hippocampus using magnetic resonance imaging. Eur J Radiol 66(2):268–273
Hahn HK, Peitgen H-O (2008) Modellgestützte Operationsplanung in der onkologischen Leberchirurgie und Transplantationschirurgie. In: Niederlag W, Lemke HU, Meixensberger J, Baumann M (eds) Modellgestützte Therapie. Health Academy, Dresden, pp 103–118
Heath DG, Hahn HK, Johnson PT, Fishman EK (2008) Automated multidetector row CT dataset segmentation with an interactive watershed transform (IWT) algorithm: Part 1. Understanding the IWT technique. J Digit Imaging 21(4):408–412
Ivanovska T, Schenk A, Dahmen U, Hahn HK, Linsen L (2008) Automatic Hepatocyte Quantification from Histological Images: Comparing Pre-smoothing Filters. In: C.P. Botha and G. Kindlmann (ed) Eurographics Workshop on Visual Computing for Biomedicine. pp 143–150
Johnson PT, Hahn HK, Heath DG, Fishman EK (2008) Automated multidetector row CT dataset segmentation with an interactive watershed transform (IWT) algorithm: Part 2. Body CT angiographic and orthopedic applications. J Digit Imaging 21(4):413–421
Klein J, Stuke H, Rexilius J, Stieltjes B, Hahn HK, Peitgen H-O (2008) Towards User-Independent DTI Quantification. SPIE Medical Imaging. SPIE, Bellingham, Washington, USA, 69142E:pp 1–8
Klein J, Stuke H, Stieltjes B, Konrad O, Hahn HK, Peitgen H-O (2008) Efficient Fiber Clustering using Parameterized Polynomials. Proceedings of SPIE Medical Imaging. SPIE, Bellingham, Washington, USA, 69182X:pp 1–9
Lukas C, Hahn HK, Bellenberg B, Hellwig K, Globas C, Schimrigk SK, Koster O, Schols L (2008) Spinal cord atrophy in spinocerebellar ataxia type 3 and 6 : impact on clinical disability. J Neurol 255(8):1244–1249
Merkel B, Harz MT, Konrad O, Hahn HK, Peitgen H-O (2008) A novel software assistant for clinical analysis of MR spectroscopy with MeVisLab. In: Giger M.L., Karssemeijer N (eds) Proc SPIE Medical Imaging. Progress in Biomedical Optics and Imaging 9(32), 69152R:pp 1–9
Rieder C, Görge HH, Ritter F, Hahn HK, Peitgen H-O (2008) Efficient Visualization of Risk Structures along Virtual Access Paths for Neurosurgical Planning. 59th Annual Meeting of the German Society of Neurosurgery (DGNC)
Rieder C, Schwier M, Hahn HK, Peitgen H-O (2008) High-Quality Multimodal Volume Visualization of Intracerebral Pathological Tissue. In: Charl Botha and Gordon Kindlmann and Wiro Niessen and Bernhard Preim (ed) Eurographics Workshop on Visual Computing for Biomedicine. Eurographics Association, pp 167–176
Schenk A, Zidowitz S, Bourquain H, Hindennach M, Hansen C, Hahn HK, Peitgen H-O (2008) Clinical relevance of model based computer-assisted diagnosis and therapy. In: Maryellen L. Giger, Nico Karssemeijer (eds) SPIE Medical Imaging. 691502:pp 1–19
Weiler F, Hahn HK, Köhn A, Friman O, Klein J, Peitgen H-O (2008) Dealing with Inaccuracies in Multimodal Neurosurgical Planning – A Preliminary Concept. Proceedings of the 22nd International Congress and Exhibition of Computer Assisted Radiology and Surgery. pp 77–78
Weiler F, Köhn A, Klein J, Rieder C, Hahn HK, Peitgen H-O (2008) Kontextbezogene Visualisierung neurochirurgischer Planungsdaten. Deutscher Röntgenkongress. 261

2007

Behrens S, Laue H, Althaus M, Boehler T, Kuemmerlen B, Hahn HK, Peitgen H-O (2007) Computer assistance for MR based diagnosis of breast cancer: present and future challenges. Comput Med Imaging Graph 31(4-5):236–247
Hahn HK, Wenzel MT, Drexl H, Zentis S, Peitgen H-O (2007) HWT – Hybrid Watershed Transform: Optimal Combination of Hierarchical Interactive and Automated Image Segmentation. SPIE Medical Imaging, Image Processing. 65120Z:pp 1–11
Harz MT, Merkel B, Boskamp T, Hahn HK (2007) Towards intuitive processing of MR spectroscopy data: A framework and prototype for clinical use. Proceedings of the RSNA. RSNA Educational Exhibit
Hildebrandt H, Lanz M, Hahn HK, Hoffmann E, Schwarze B, Schwendemann G, Kraus JA (2007) Cognitive training in MS: effects and relation to brain atrophy. Restor Neurol Neurosci 25(1):33–43
Huff S, Laun FB, Stieltjes B, Klein J, Hahn HK, Schad LR (2007) Optimized DTI for fibre bundles of known predominant orientation. Proceedings of Joint Annual Meeting ISMRM-ESMRMB. MIRA Digital Publishing, 1505
Köhn A, Weiler F, Klein J, Konrad O, Hahn HK, Peitgen H-O (2007) State-of-the-Art Computer Graphics in Neurosurgical Planning and Risk Assessment. In: Cignoni P, Sochor J (eds) Eurographics Short Papers and Medical Prize Awards. pp 117–120
Klein J, Bittihn P, Ledochowitsch P, Hahn HK, Konrad O, Rexilius J, Peitgen H-O (2007) Grid-Based Spectral Fiber Clustering. In: Cleary KR, Miga MI (eds) SPIE Medical Imaging. SPIE, Bellingham, 65091E:pp 1–10
Klein J, Erhard P, Hermann S, Konrad O, Hahn HK, Leibfritz D, Peitgen H-O (2007) Resolution-Dependent Differences in Fiber Tracking and Quantification. Proceedings of Joint Annual Meeting ISMRM-ESMRMB. MIRA Digital Publishing, 1555
Klein J, Hermann S, Konrad O, Hahn HK (2007) Automatic Quantification of DTI Parameters along Fiber Bundles. In: Horsch A, Deserno TM, Handels H, Meinzer H-P, Tolxdorff T (eds) Bildverarbeitung für die Medizin. Proc BVM, pp 272–276
Klein J, Schlüter M, Rexilius J, Konrad O, Erhard P, Stieltjes B, Althaus M, Dreher W, Leibfritz D, Hahn HK, Peitgen H-O (2007) Uncertainty and Reproducibility of Quantitative DTI and Fiber Tracking of the Human Brain. Topics in Advanced Imaging 6:61–64
Klein J, Vilanova A, Ledochowitsch P, Bittihn P, Hahn HK, Konrad O, Rexilius J, Peitgen H-O (2007) Improving Interaction and Perception of Brain Structure using Fiber Clustering. SPIE Newsroom. SPIE, Bellingham, Washington, USA, pp 1–3
Lanz M, Hahn HK, Hildebrandt H (2007) Brain atrophy and cognitive impairment in multiple sclerosis: a review. J Neurol 254(2):II 43–48
Laue H, Althaus M, Behrens S, Hahn HK, Peitgen H-O (2007) Dependency of parameter estimates for the Tofts model on temporal sampling rate and on bolus arrival time. Proceedings of the 15th Scientific Meeting of the International Society for Magnetic Resonance in Medicine. 1722
Machilsen B, d'Agostino E, Maes F, Vandermeulen D, Hahn HK, Lagae L, Stiers P (2007) Linear normalization of MR brain images in pediatric patients with periventricular leukomalacia. NeuroImage 35(2):686–697
Müller-Horvat C, Plathow C, Ludescher B, Lichy MP, Canda V, Zindel C, Hahn HK, Peitgen H-O, Kuhnigk J-M, Claussen CD, Schlemmer HP (2007) Generating Statements at Whole-Body Imaging with a Workflow-Optimized Software Tool – First Experiences with Multireader Analysis. RöFo Fortschr Röntgenstr 179(7):721–727
Rexilius J, Hahn HK, Klein J, Lentschig MG, Peitgen H-O (2007) Multispectral Brain Tumor Segmentation based on Histogram Model Adaptation. Proceeding of SPIE Medical Imaging. 65140V:pp 1–10
Schimrigk SK, Bellenberg B, Schlueter M, Stieltjes B, Drescher R, Rexilius J, Lukas C, Hahn HK, Przuntek H, Koster O (2007) Diffusion tensor imaging-based fractional anisotropy quantification in the corticospinal tract of patients with amyotrophic lateral sclerosis using a probabilistic mixture model. Am J Neuroradiol 28(4):724–730

2006

Dukatz T, Sure U, Ivinska-Zelder J, Beyer T, Hahn HK, Klein J, Benes L, Bertalanffy H (2006) White Matter Trajectories in Pre- and Postoperative DTI Examinations and Fiber Tracking for Patients with Brain Stem Cavernomas. Proc Soc Clinical Neurophysiology. Essen, p e28
Giesel FL, Hahn HK, Thomann PA, Widjaja E, Wignall E, von Tengg-Kobligk H, Pantel J, Griffiths PD, Peitgen H-O, Schroder J, Essig M (2006) Temporal horn index and volume of medial temporal lobe atrophy using a new semiautomated method for rapid and precise assessment. AJNR Am J Neuroradiol 27(7):1454–1458
Gluer C-C, Barkmann R, Hahn HK, Majumdar S, Eckstein F, Nickelsen TN, Bolte H, Dicken V, Heller M (2006) Parametrische biomedizinische Bildgebung--was macht die Qualitat quantitativer radiologischer Verfahren aus? RöFo Fortschr Röntgenstr 178(12):1187–1201
Hahn HK, Klein J, Nimsky C, Rexilius J, Peitgen H-O (2006) Uncertainty in diffusion tensor based fibre tracking. Acta Neurochir Suppl 98:33–41
Hahn HK, Wenzel MT, Konrad-Verse O, Peitgen H-O (2006) A Minimally-Interactive Watershed Algorithm Designed for Efficient CTA Bone Removal. Proc CVAMIA. pp 178–189
Hildebrandt H, Hahn HK, Kraus JA, Schulte-Herbruggen A, Schwarze B, Schwendemann G (2006) Memory performance in multiple sclerosis patients correlates with central brain atrophy. Mult Scler 12(4):428–436
Klein J, Hahn HK, Rexilius J, Erhard P, Althaus M, Leibfritz D, Peitgen H-O (2006) Efficient Visualization of Fiber Tracking Uncertainty based on Complex Gaussian Noise. Proceedings of the 14th ISMRM Scientific Meeting & Exhibition. Seattle, USA, 2753
Klein J, Ritter F, Hahn HK, Rexilius J, Peitgen H-O (2006) Brain Structure Visualization using Spectral Fiber Clustering. In: Finnegan J (ed) Proceedings of SIGGRAPH
Koehn A, Hahn HK, Klein J, Breitenborn J, Siems U, Boehler T, Berghorn W, Simonotto E, Link F, Rexilius J, Lund R, Jürgens H, Peitgen H-O (2006) A Workflow Optimized Software Platform for Multimodal Neurosurgical Planning and Monitoring. Proceeding CURAC. pp 44–46
Rexilius J, Kuhnigk JM, Hahn HK, Peitgen H-O (2006) An Application Framework for Rapid Prototyping of Clinically Applicable Software Assistants. In: Hochberger C, Liskowsky R (eds) Lecture Notes in Informatics. Lecture Notes in Informatics P-93, pp 522–528
Stieltjes B, Schlüter M, Didinger B, Weber M-A, Hahn HK, Parzer P, Rexilius J, Konrad-Verse O, Peitgen H-O, Essig M (2006) Diffusion tensor imaging in primary brain tumors: reproducible quantitative analysis of corpus callosum infiltration and contralateral involvement using a probabilistic mixture model. Neuroimage 31(2):531–542

2005

Boskamp T, Hahn HK, Hindennach M, Oeltze S, Preim B, Zidowitz S, Peitgen H-O (2005) Geometrical and Structural Analysis of Vessel Systems in 3D Medical Image Datasets. In: Leondes CT (ed) Medical Imaging Systems Technology. World Scientific, New Jersey, pp 1–60
Giesel FL, Wustenberg T, Bongers A, Weber MA, Zechmann C, Baudendistel KT, Tengg-Kobligk H, Hahn HK, Essig M, Kauczor HU (2005) MR-basierte Methoden der funktionellen Bildgebung des zentralen Nervensystems. RöFo Fortschr Röntgenstr 177(5):714–730
Hahn HK, Georg M, Peitgen H-O (2005) Fractal Aspects of Three-Dimensional Vascular Constructive Optimization. In: Losa GA, Merlini D, Nonnenmacher TF, Weibel ER (eds) Fractals in Biology and Medicine. Birkhäuser, Basel, pp 55–66
Rexilius J, Hahn HK, Schlüter M, Bourquain H, Peitgen H-O (2005) Evaluation of accuracy in MS lesion volumetry using realistic lesion phantoms. Acad Radiol 12(1):17–24
Schlüter M, Stieltjes B, Hahn HK, Rexilius J, Konrad-Verse O, Peitgen H-O (2005) Detection of tumour infiltration in axonal fibre bundles using diffusion tensor imaging. Int J Med Robot Comput Assist Surg 1(3):80–86
Schlüter M, Konrad-Verse O, Hahn HK, Stieltjes B, Rexilius J, Peitgen H-O (2005) White Matter Lesion Phantom for Diffusion Tensor Data and Its Application to the Assessment of Fiber Tracking. SPIE Medical Imaging. pp 835–844

2004

Apelt D, Preim B, Hahn HK, Strauss G (2004) Bildanalyse und Visualisierung für die Planung von Nasennebenhöhlen-Operationen. In: Tolxdorff T, Braun J, Handels H, Horsch A, Meinzer H-P (eds) Bildverarbeitung für die Medizin. Proc BVM, pp 194–198
Drexl J, Knappe V, Hahn HK, Lehmann K, Frericks BB, Shin H, Peitgen H-O (2004) Accuracy analysis of vessel segmentation for a LITT dosimetry planning system. Medical Robotics, Navigation and Visualization. Proc MRNV, pp 204–212
Hahn HK, Jolly B, Lee M, Krastel D, Rexilius J, Drexl J, Schlüter M, Terwey B, Peitgen H-O (2004) How Accurate is Brain Volumetry? A Methodological Evaluation. In: Barillot C, Haynor DR, Hellier P (eds) Medical Image Computing and Computer-Assisted Intervention. Springer, Berlin, pp 335–342
Hahn HK, Millar WS, Klinghammer O, Durkin MS, Tulipano PK, Peitgen H-O (2004) A Reliable and Efficient Method for Cerebral Ventricular Volumetry in Pediatric Neuroimaging. Methods Inf Med 43(4):376–382
Hahn HK, Rexilius J, Schlüter M, Terwey B, Stieltjes B, Giesel F, Peitgen H-O (2004) Fast and Robust Quantification of Parahippocampal Atrophy via Temporal Horn Index. In: Wittenberg T, et al. (eds) Bildverarbeitung für die Medizin. Proc BVM, pp 371–375
Heverhagen JT, Hahn HK, Wegmann M, Herz U, Shaffer Whitaker CD, Matschl V, Alfke H (2004) Volumetric analysis of mice lungs in a clinical magnetic resonance imaging scanner. Magn Reson Mater Phy 17(2):80–85
Lukas C, Hahn HK, Bellenberg B, Rexilius J, Schmid G, Schimrigk SK, Przuntek H, Koster O, Peitgen H-O (2004) Sensitivity and reproducibility of a new fast 3D segmentation technique for clinical MR-based brain volumetry in multiple sclerosis. Neuroradiology 46(11):906–915
Rexilius J, Hahn HK, Schlüter M, Kohle S, Bourquain H, Böttcher J, Peitgen H-O (2004) A Framework for the Generation of Realistic Brain Tumor Phantoms and Applications. In: Barillot C, Haynor DR, Hellier P (eds) Medical Image Computing and Computer Assisted Intervention. LNCS 3217, pp 243–250
Schlüter M, Stieltjes B, Hahn HK, Rexilius J, Konrad-Verse O., Peitgen HO (2004) Early Stage Detection of Tumor Infiltration in White Matter Fiber Bundles Using Diffusion Tensor Imaging. Proc CURAC
Schlüter M, Stieltjes B, Rexilius J, Hahn HK, Peitgen H-O (2004) Unique Planar Color Coding of Fiber Bundles and Its Application to Fiber Integrity Quantification. International Symposium on Biomedical Imaging. IEEE, pp 900–903
Segonne F, Dale AM, Busa E, Glessner M, Salat D, Hahn HK, Fischl B (2004) A hybrid approach to the skull stripping problem in MRI. Neuroimage 22(3):1060–1075

2003

Hahn HK, Peitgen H-O (2003) IWT – Interactive Watershed Transform: A Hierarchical Method for Efficient Interactive and Automated Segmentation of Multidimensional Gray-Scale Images. In: Sonka M, Fitzpatrick JM (eds) Proceedings of SPIE Medical Imaging. SPIE, Bellingham, pp 643–653
Hahn HK, Rexilius J, Schlüter M, Stieltjes B, Raab P, Giesel F, Peitgen HO (2003) Flexible Research and Development Platform for Multimodal Neurosurgical Planning and Therapy Monitoring. Proc CURAC
Hahn HK, Evertsz CJG, Fasel JHD, Peitgen H-O (2003) Fractal Properties, Segment Anatomy, and Interdependence of the Human Portal Vein and the Hepatic Vein in 3D. Fractals 11(1):53–62
Hahn HK, Link F, Peitgen H-O (2003) Concepts for Rapid Application Prototyping in Medical Image Analysis and Visualization. Simulation und Visualisierung. SCS-Verlag, Ghent, pp 283–298
Kuhnigk JM, Hahn HK, Hindennach M, Dicken V, Krass S, Peitgen H-O (2003) 3D-Lungenlappen-Segmentierung durch Kombination von Region Growing, Distanz- und Wasserscheiden-Transformation. In: Wittenberg T, et al. (eds) Bildverarbeitung für die Medizin. Springer, Berlin, pp 146–150
Kuhnigk JM, Hahn HK, Hindennach M, Dicken V, Krass S, Peitgen H-O (2003) Lung Lobe Segmentation by Anatomy-Guided 3D Watershed Transform. In: Sonka M, Fitzpatrick JM (eds) Proceedings of SPIE Medical Imaging. SPIE, Bellingham, pp 1482–1490
Rexilius J, Hahn HK, Bourquain H, Peitgen H-O (2003) Ground Truth in MS Lesion Volumetry – A Phantom Study. Medical Image Computing and Computer-Assisted Intervention. Springer, Berlin, pp 546–553
Stieltjes B, Schlüter M, Hahn HK, Wilhelm T, Essig M (2003) Diffusions-Tensor-Bildgebung. Theorie, Sequenzoptimierung und Anwendungen bei Morbus Alzheimer. Radiologe 43(7):562–565
Wiese M, Willburger RE, Schmidt K, Stockheim M, Hahn HK, Rubenthaler F, Haaker R (2003) Total Knee Replacement – First Results of a CT based measurement system. In: Langlotz F, Davies BL, Bauer A (eds) Computer Assisted Orthopaedic Surgery. Steinkopff, Darmstadt, 398

2002

Boskamp T, Hahn HK, Gerhards A, Raab P, Mildenberger P, Peitgen H-O (2002) Semi-automatic vessel segmentation using a combined region growing/watershed-method. Radiology. 362
Hahn HK, Millar WS, Durkin MS, Klinghammer O, Peitgen H-O (2002) Cerebral Ventricular Volumetry in Pediatric Neuroimaging. Bildverarbeitung für die Medizin. Springer, Berlin, pp 59–62
Hahn HK, Millar WS, Durkin MS, Klinghammer O, Tulipano PK, Peitgen HO (2002) A New Method for Semi-Automatic Volumetry of Cerebral Ventricles in Pediatric Neuroimaging. Proceedings Internationale Society of Magneto Resonance Medicine. 358
Schubert A, Hahn HK, Peitgen H-O (2002) Robuste vollautomatische Gehirnsegmentierung basierend auf einer 3D-Wasserscheidentransformation. Bildverarbeitung für die Medizin. Proc BVM, pp 193–196
Spindler W, Preim B, Hahn HK, Bourquain H, Peitgen H-O (2002) Visualization for Intervention Planning. Radiology. 751

2001

Hahn HK, Deimling M, Lentschig MG, Terwey B, Peitgen HO (2001) Ultrafast MRI-based Volumetry of Intracranial Liquor Spaces. NeuroImage. Proc. HBM, Neuroimage 13(6, part 2), S140
Hahn HK, Lentschig MG, Deimling M, Terwey B, Peitgen H-O (2001) MRI Based Volumetry of Intra- and Extracerebral CSF Spaces. Computer Assisted Radiology and Surgery. Elsevier, Amsterdam, pp 401–407
Hahn HK, Lentschig MG, Terwey B, Peitgen H-O (2001) Clinical MRI Based Volumetry: The Cerebral Ventricles. Medical Image Computing and Computer Assisted Intervention. Springer, Berlin, pp 1291–1292
Hahn HK, Preim B, Selle D, Peitgen H-O (2001) Visualization and Interaction Techniques for the Exploration of Vascular Structures. IEEE Visualization. pp 395–402

2000

Hahn HK, Peitgen H-O (2000) The Skull Stripping Problem in MRI Solved by a Single 3D Watershed Transform. Medical Image Computing and Computer-Assisted Intervention. Springer, Berlin, pp 129–145
Hahn HK, Selle D, Evertsz CJG, Peitgen H-O (2000) Interaktive Visualisierung von Gefäßsystemen auf der Basis von Oberflächenprimitiven. Simulation und Visualisierung. SCS-Verlag, Ghent, pp 105–118
Hahn HK, Selle D, Evertsz CJG, Peitgen H-O (2000) Strukturanalyse und Morphometrie interagierender Gefäßsysteme am Beispiel der menschlichen Leber. Bildverarbeitung für die Medizin. Springer, Berlin, pp 324–328